Satiating diet for weight loss and appetite control in obese individuals
Non-restrictive Approach to Facilitate Appetite Control and Long-term Body Weight Loss in Individuals With Obesity: Can we do Better?
This study is testing if a new filling diet can help people with obesity lose weight and control their appetite better than traditional dieting methods.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 234 (estimated) |
| Ages | 18 Years to 50 Years |
| Sex | All |
| Sponsor | Laval University Academic / other |
| Locations | 1 site (Québec, Quebec) |
| Trial ID | NCT05141526 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effects of a non-restrictive satiating diet on appetite control and body weight loss in individuals with obesity. It involves an 18-month randomized controlled trial with three groups: one receiving a non-restrictive satiating intervention, another undergoing a conventional restrictive diet followed by the satiating intervention, and a control group following minimal healthy guidelines. The trial aims to determine if the satiating diet can help maintain weight loss and prevent appetite increases after conventional dieting. Participants will be monitored for changes in body weight and appetite throughout the study.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18-50 with a BMI between 30 and 40 kg/m2 and specific waist circumference measurements.
Not a fit: Patients with significant weight fluctuations, certain chronic conditions, or those on medications affecting appetite may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could provide a sustainable method for weight loss and appetite management in individuals with obesity.
How similar studies have performed: Other studies have shown promise with non-restrictive dietary interventions, suggesting potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * individuals with a BMI ≥30 and \<40 kg/m2 * aged between 18-50 years * waist circumference \>102 cm in men and \>88 cm in women. Exclusion Criteria: * taking medications that could influence appetite or body weight (e.g. thyroid replacement therapy, sulfonylureas and glucocorticoids) * being treated with insulin for type 2 diabetes * large body weight fluctuations (\>4 kg over last two months) * characterized by high restraint behaviour (score \>12, measured with the TFEQ) * history of an eating disorder (e.g. binge eating disorder) using the EDE questionnaire * performing \>150 min of moderate-vigorous intensity physical activity/week * use of nutritional supplements (multivitamins, calcium, protein, fibre); 8) smoking, drugs or alcohol (\>2 drinks/d) * consumption of \>5 cups of coffee/d * (pre)menopausal or pregnant women * diagnosis of chronic diseases, acute infections or gastric problems (e.g. ulcers) * food allergies/intolerances to ingredients/foods in the satiating intervention * having a pacemaker (for fMRI) * taking sedatives or sleeping pills * symptoms of depression (\>20 on the BDI).
Where this trial is running
Québec, Quebec
- Department of Physical Education — Québec, Quebec, Canada (Recruiting)
Study contacts
- Study coordinator: Vicky Drapeau, PhD
- Email: vicky.drapeau@fse.ulaval.ca
- Phone: 4186562131
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.