Sarcopenia and related risk factors in people with multiple sclerosis
Official title: Sarcopenia and Related Factors in Patients With Multiple Sclerosis
Run by Selcuk University · NCT07116070 · Data updated 2026-11-12
This study will see how common low muscle mass (sarcopenia) and related factors are in adults with multiple sclerosis.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 90 (estimated) |
| Sponsor | Selcuk University Academic / other |
| Locations | 1 site (Konya, Selcuklu) |
| Status | Recruiting |
| Started | June 1, 2025 |
| Main results expected | January 20, 2026 |
| Study ends | March 20, 2026 |
| Registry record updated | August 11, 2025 |
| Trial ID | NCT07116070 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (≥18) with a neurologist-confirmed multiple sclerosis diagnosis who are in a stable phase (no relapse in the past 3 months), able to walk (EDSS ≤6.5), and able to give informed consent.
✕Probably not a fit
People with other neuromuscular diseases, recent major surgery or trauma, recent corticosteroid- or immunosuppressive-related muscle loss, systemic diseases that cause muscle wasting, or who are pregnant or breastfeeding are excluded and unlikely to benefit from this protocol.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is an observational clinical assessment program conducted at Selcuk University’s MS Life Center that measures muscle mass, muscle strength, physical performance, and nutritional indicators in adults with multiple sclerosis. Eligible participants are ambulatory, neurologist-diagnosed adults in a stable phase of disease who can give informed consent. The protocol uses standardized clinical assessments (including EDSS screening, body composition and strength testing, and nutrition questionnaires) to identify sarcopenia and associated contributors. Results will describe prevalence and correlate muscle status with disability, physical performance, and nutritional factors.
Why it matters
Potential benefit: If successful, the findings could help clinicians identify MS patients at risk for muscle loss so they can offer targeted rehabilitation and nutritional support to preserve function.
How similar studies have gone: Prior research has reported a high prevalence of sarcopenia in people with MS and links to poorer physical performance and quality of life, but prevalence estimates vary and comprehensive data are limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Being 18 years of age or older, * Having been diagnosed with Multiple Sclerosis (confirmed by a neurologist), * Being in a stable phase of the disease (having not had an attack in the last 3 months), * Having preserved walking ability (EDSS score ≤6.5), * Being able to give informed consent to participate in the study. Exclusion Criteria: * Having another neuromuscular disease. * Having developed significant muscle loss within the last 6 months due to use of corticosteroids or immunosuppressive therapy. * Having systemic diseases that can cause muscle loss, such as cancer, rheumatic diseases, or severe metabolic disorders. * Having undergone major surgery or a history of serious trauma within the last 3 months. * Being pregnant or breastfeeding.
Where it's running
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Selcuk University Faculty of Medicine Hospital MS Life Center
Konya, Selcuklu, Turkey (Türkiye) Recruiting
Study contacts
- Principal investigator: İsmail ÖZSOY, Assoc. Prof. Dr. — Selcuk University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Konya, Türkiye
- Study coordinator: Mehmet K ALTUNOK, PHD(c) in PT
- Email: mehmetkaan.altunok@selcuk.edu.tr
- Phone: 5558175133
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.