Clinical trial Recruiting at 1 site Observational

San Raffaele registry for adults with eosinophilic esophagitis

Official title: Prospective Registry of EoSinophilic esOphagitis (PRESO)

Run by IRCCS San Raffaele · NCT06443346 · Data updated 2026-11-12

This registry will collect clinical, endoscopic, and biopsy information from adults with eosinophilic esophagitis who are referred to the San Raffaele Motility and EoE Unit.

More Eosinophilic Esophagitis trials

Quick facts

Study typeObservational
SexAll
Enrollment1000 (estimated)
SponsorIRCCS San Raffaele
Academic / other
Locations1 site (Milan, Lombardy)
StatusRecruiting
StartedJune 1, 2024
Main results expectedDecember 31, 2034
Study endsDecember 31, 2044
Registry record updatedJuly 30, 2025
Trial IDNCT06443346 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults (age >18) with a guideline-based diagnosis of eosinophilic esophagitis who are referred to the Motility and EoE Unit at San Raffaele and can give informed consent are ideal candidates.

Probably not a fit

People without a clear EoE diagnosis, those under 18, or those unwilling to provide informed consent will not be included and are unlikely to benefit from this registry.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective, observational registry enrolling adults (over 18) diagnosed with eosinophilic esophagitis and referred to the Motility and EoE Unit at IRCCS San Raffaele in Milan. Participants provide informed consent and their standard-of-care clinical, endoscopic, histologic, and related data are recorded longitudinally. No experimental treatments are administered as part of the registry; patients continue usual clinical care. The collected data will be used to describe disease features, support future retrospective or prospective studies, and foster national and international collaborations.

Why it matters

Potential benefit: If successful, the registry could improve understanding of disease patterns and treatment outcomes and help design better-targeted research and care pathways for EoE patients.

How similar studies have gone: Prospective registries in EoE and other gastrointestinal diseases have been used successfully to define phenotypes, outcomes, and research priorities, so this approach is established rather than novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Participant is willing and able to give informed consent for participation in the study.
2. The medical product is the standard of care for the patient or the participant is taking the medicinal product according to clinical practice
3. Being diagnosed with EoE as per guidelines of the disease

Exclusion Criteria:

1. No clear diagnosis of EoE
2. Not willing to provide informed consent to the inclusion in the registry

Where it's running

  • IRCCS San Raffaele
    Milan, Lombardy, Italy
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.