Sacral canal block to control blood pressure during hip replacement in older adults
Official title: Sacral Canal Block for Hip Replacement the Efficacy and Safety of Controlled Intraoperative Hypotension:a Single-center, Prospective, Randomized Controlled Study
Run by General Hospital of Ningxia Medical University · NCT07064434 · Data updated 2026-11-12
This will test whether giving a sacral canal block before hip replacement helps safely lower blood pressure during surgery for people over 45.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 45 Years and up |
| Sex | All |
| Enrollment | 80 (estimated) |
| Sponsor | General Hospital of Ningxia Medical University Academic / other |
| Locations | 1 site (Yinchuan, Ningxia) |
| Status | Recruiting |
| Started | November 1, 2024 |
| Main results expected | October 30, 2025 |
| Study ends | October 30, 2025 |
| Registry record updated | July 14, 2025 |
| Trial ID | NCT07064434 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are people over 45 years old with ASA physical status II–III, BMI 18–35 kg/m², scheduled for hip replacement, able to consent, and without contraindications to sacral canal block.
✕Probably not a fit
Patients under 45, those with contraindications to sacral canal block, severe communication barriers, or outside the specified ASA/BMI ranges are unlikely to benefit from this protocol.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study compares using a sacral canal block plus general anesthesia versus general anesthesia alone for older adults undergoing hip replacement. The sacral canal block is performed about 30 minutes before incision, and investigators record time to reach target controlled hypotension, duration at target pressure, and blood pressure variability. Outcomes include intraoperative blood loss, surgeon satisfaction, and a range of safety measures such as limb tissue oxygen saturation, peripheral perfusion index, unexpected hypotension, heart rate variability, pulse oximetry, and block-related complications. The trial is conducted at the General Hospital of Ningxia Medical University in Yinchuan, Ningxia.
Why it matters
Potential benefit: If successful, this approach could offer a safer and more controlled way to lower blood pressure during hip replacement and may reduce blood loss and related complications for older patients.
How similar studies have gone: Regional neuraxial blocks have been used to facilitate controlled hypotension in orthopedic surgery, but published data specifically on sacral canal block for this purpose are limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Over 45 years old; 2. ASA Grade II - III; 3. BMI 18-35kg/㎡; 4. Agree to participate in this study and sign the informed consent form. Exclusion Criteria: 1. Those who refuse to participate in the experiment; 2. Those who suffer from language or hearing impairments and are unable to communicate; 3. Those with contraindications for sacral canal block.
Where it's running
-
General hospital of Ningxia medical university
Yinchuan, Ningxia, China Recruiting
Study contacts
- Study coordinator: Xinli Ni, MD
- Email: xinlini6@nyfy.com.cn
- Phone: 13909586966
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
PECS II vs SPSIP nerve blocks for pain after mastectomy
This study tests whether two ultrasound-guided nerve blocks (PECS II and SPSIP) differ in how much opioid patients need after mastectomy.
-
Palatal Shield Technique to Reduce Pain and Improve Healing After Free Gingival Graft
This randomized trial tests whether a collagen sponge with a protective palatal shield made of flowable resin helps reduce pain and improve healing after free gingival graft harvest.
-
Perfusion Index to Measure Postoperative Pain in Kids After Adenotonsillectomy
This study tests whether the perfusion index can reliably reflect pain levels in children aged 1–12 after adenotonsillectomy, comparing standard care with an added glossopharyngeal nerve block.
-
Anterior Knee Nerves Block vs Femoral Nerve Block for Knee Arthroscopy
This trial tests whether an anterior nerves of the knee (ANK) block provides similar pain relief to a femoral nerve block after knee arthroscopy in adults, aiming to reduce quadriceps weakness.
-
Natural Biopolymer-Based Irrigant for Root Canal Cleaning
This trial tests a chitosan nanoparticle irrigant to improve cleaning and disinfection in single-rooted teeth with asymptomatic pulp necrosis undergoing endodontic treatment.
-
Postoperative Pain Trajectories After Endometriosis Surgery
This study tests how pain changes after endometriosis surgery and whether perioperative pain testing can predict who will have ongoing pain.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.