Clinical trial Recruiting at 1 site Interventional Ages 45 and up

Sacral canal block to control blood pressure during hip replacement in older adults

Official title: Sacral Canal Block for Hip Replacement the Efficacy and Safety of Controlled Intraoperative Hypotension:a Single-center, Prospective, Randomized Controlled Study

Run by General Hospital of Ningxia Medical University · NCT07064434 · Data updated 2026-11-12

This will test whether giving a sacral canal block before hip replacement helps safely lower blood pressure during surgery for people over 45.

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Quick facts

Study typeInterventional
Ages45 Years and up
SexAll
Enrollment80 (estimated)
SponsorGeneral Hospital of Ningxia Medical University
Academic / other
Locations1 site (Yinchuan, Ningxia)
StatusRecruiting
StartedNovember 1, 2024
Main results expectedOctober 30, 2025
Study endsOctober 30, 2025
Registry record updatedJuly 14, 2025
Trial IDNCT07064434 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are people over 45 years old with ASA physical status II–III, BMI 18–35 kg/m², scheduled for hip replacement, able to consent, and without contraindications to sacral canal block.

Probably not a fit

Patients under 45, those with contraindications to sacral canal block, severe communication barriers, or outside the specified ASA/BMI ranges are unlikely to benefit from this protocol.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study compares using a sacral canal block plus general anesthesia versus general anesthesia alone for older adults undergoing hip replacement. The sacral canal block is performed about 30 minutes before incision, and investigators record time to reach target controlled hypotension, duration at target pressure, and blood pressure variability. Outcomes include intraoperative blood loss, surgeon satisfaction, and a range of safety measures such as limb tissue oxygen saturation, peripheral perfusion index, unexpected hypotension, heart rate variability, pulse oximetry, and block-related complications. The trial is conducted at the General Hospital of Ningxia Medical University in Yinchuan, Ningxia.

Why it matters

Potential benefit: If successful, this approach could offer a safer and more controlled way to lower blood pressure during hip replacement and may reduce blood loss and related complications for older patients.

How similar studies have gone: Regional neuraxial blocks have been used to facilitate controlled hypotension in orthopedic surgery, but published data specifically on sacral canal block for this purpose are limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Over 45 years old;
2. ASA Grade II - III;
3. BMI 18-35kg/㎡;
4. Agree to participate in this study and sign the informed consent form.

Exclusion Criteria:

1. Those who refuse to participate in the experiment;
2. Those who suffer from language or hearing impairments and are unable to communicate;
3. Those with contraindications for sacral canal block.

Where it's running

  • General hospital of Ningxia medical university
    Yinchuan, Ningxia, China
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.