Sacral canal block to control blood pressure during hip replacement in older adults
Sacral Canal Block for Hip Replacement the Efficacy and Safety of Controlled Intraoperative Hypotension:a Single-center, Prospective, Randomized Controlled Study
This will test whether giving a sacral canal block before hip replacement helps safely lower blood pressure during surgery for people over 45.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 80 (estimated) |
| Ages | 45 Years and up |
| Sex | All |
| Sponsor | General Hospital of Ningxia Medical University Academic / other |
| Locations | 1 site (Yinchuan, Ningxia) |
| Trial ID | NCT07064434 on ClinicalTrials.gov |
What this trial studies
This interventional study compares using a sacral canal block plus general anesthesia versus general anesthesia alone for older adults undergoing hip replacement. The sacral canal block is performed about 30 minutes before incision, and investigators record time to reach target controlled hypotension, duration at target pressure, and blood pressure variability. Outcomes include intraoperative blood loss, surgeon satisfaction, and a range of safety measures such as limb tissue oxygen saturation, peripheral perfusion index, unexpected hypotension, heart rate variability, pulse oximetry, and block-related complications. The trial is conducted at the General Hospital of Ningxia Medical University in Yinchuan, Ningxia.
Who should consider this trial
Good fit: Ideal candidates are people over 45 years old with ASA physical status II–III, BMI 18–35 kg/m², scheduled for hip replacement, able to consent, and without contraindications to sacral canal block.
Not a fit: Patients under 45, those with contraindications to sacral canal block, severe communication barriers, or outside the specified ASA/BMI ranges are unlikely to benefit from this protocol.
Why it matters
Potential benefit: If successful, this approach could offer a safer and more controlled way to lower blood pressure during hip replacement and may reduce blood loss and related complications for older patients.
How similar studies have performed: Regional neuraxial blocks have been used to facilitate controlled hypotension in orthopedic surgery, but published data specifically on sacral canal block for this purpose are limited.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Over 45 years old; 2. ASA Grade II - III; 3. BMI 18-35kg/㎡; 4. Agree to participate in this study and sign the informed consent form. Exclusion Criteria: 1. Those who refuse to participate in the experiment; 2. Those who suffer from language or hearing impairments and are unable to communicate; 3. Those with contraindications for sacral canal block.
Where this trial is running
Yinchuan, Ningxia
- General hospital of Ningxia medical university — Yinchuan, Ningxia, China (Recruiting)
Study contacts
- Study coordinator: Xinli Ni, MD
- Email: xinlini6@nyfy.com.cn
- Phone: 13909586966
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.