Roxadustat for treating anemia and improving bone and mental health in hemodialysis patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effects of Roxadustat, an oral medication, on anemia and its potential benefits for bone health and mental well-being in patients undergoing hemodialysis for end-stage kidney disease. The study aims to assess changes in bone mineral density, psychological symptoms of depression and anxiety, and nerve and muscle function through various tests and questionnaires. A total of 46 patients will be enrolled to evaluate the broader impacts of Roxadustat beyond its primary use for anemia treatment.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* The age of the patient is more than 18.
* Patients who are willing to sign informed consent.
* Patients with ESKD on chronic hemodialysis for more than 3 months.

Exclusion Criteria:

* Current pregnancy or lactation.
* Patients with pre-existing malignancy.
* patients with psychosis.
* Known history of hematological disorders or other causes of anemia other than CKD.
* Taking medications that may significantly affect or interact with bone metabolism such as osteo-anabolics or bone resorptives during the last 6 months.

Where it's running

• Urology and Nephrology Center, Mansoura University
  Al Mansurah, Dakahliya, Egypt Recruiting

Study contacts

• Study coordinator: Mostafa I Alaskary, M.Sc
• Email: drmostafa2110@gmail.com
• Phone: +201017178892

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.