Routine screening and support for emotional health in adults with type 2 diabetes

ARISE: Achieving Routine Intervention and Screening for Emotional Health: Randomized Controlled Trial

Not applicable Interventional University of Chicago · NCT06887049

This project will test whether routine screening for diabetes-related emotional distress plus brief clinic training helps adults with type 2 diabetes and A1C over 8% feel less distressed and manage their diabetes better.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment1250 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of Chicago Academic / other
Locations1 site (Chicago, Illinois)
Trial IDNCT06887049 on ClinicalTrials.gov

What this trial studies

Patients at participating University of Chicago clinics with type 2 diabetes and A1C > 8% will be screened for diabetes distress using a standardized instrument. Clinics will implement the ARISE Learning Community diabetes distress screening and intervention or receive an ARISE Enhanced Care brief training to help clinicians address distress. Outcomes include changes in diabetes distress scores, self-care behaviors, and clinical measures such as A1C. The project emphasizes improving detection and treatment of diabetes-related emotional burden, particularly in populations with higher prevalence of distress.

Who should consider this trial

Good fit: Ideal candidates are adults (18+) with type 2 diabetes who receive care at a participating clinic and have an A1C above 8% and are not pregnant.

Not a fit: Patients who are pregnant, have type 1 diabetes, have A1C ≤ 8%, or do not receive care at a participating clinic are unlikely to benefit from this program.

Why it matters

Potential benefit: If successful, routine screening combined with targeted clinic support could lower diabetes-related distress, improve self-care, and modestly improve blood sugar control.

How similar studies have performed: Previous studies have used standardized diabetes distress screening and some intervention trials have shown reductions in distress, although routine screening is not yet widely implemented.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patient at a participating clinic
* Type 2 diabetes
* Adult (18 years or older)
* A1C \> 8%

Exclusion Criteria:

* Pregnant

Where this trial is running

Chicago, Illinois

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Type 2 Diabetes MellitusDiabetes Distressdiabetes distress screening
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.