Robot-assisted versus manual ultrasound-guided carpal tunnel injection

Ultrasound-Guided Carpal Tunnel Infiltration: Comparison Between the Manual Method and a Robot-Assisted Method - A Pilot, Comparative, Randomized Study

Not applicable Interventional Centre Hospitalier Régional d'Orléans · NCT07334964

This study will test whether using a robotic arm to hold the ultrasound probe makes steroid injections for adults with carpal tunnel syndrome easier, safer, or more accurate than the usual manual method.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment20 (estimated)
Ages18 Years to 75 Years
SexAll
SponsorCentre Hospitalier Régional d'Orléans Academic / other
Locations1 site (Orléans)
Trial IDNCT07334964 on ClinicalTrials.gov

What this trial studies

Adults with clinically diagnosed moderate to severe carpal tunnel syndrome who need a corticosteroid injection will receive an ultrasound-guided injection with either the usual manual probe holding or with the ultrasound probe held by a robotic arm. The robotic arm is used to maintain probe position during the injection, removing the need for a third person to hold the probe. Follow-up at day 7, day 28 and three months will collect pain VAS scores, the Boston Carpal Tunnel Questionnaire, and patient satisfaction by phone, teleconsultation, or clinic visit. The trial will record feasibility, safety events, and measures of injection accuracy to inform a larger future study.

Who should consider this trial

Good fit: Adults aged 18–75 with a clinical diagnosis of carpal tunnel syndrome, a baseline pain VAS ≥ 4, and a clinical indication for corticosteroid injection are ideal candidates.

Not a fit: Patients with prior carpal tunnel surgery, thenar eminence atrophy, recent injection in the affected wrist, active infection, allergy to study materials, pregnancy, or other listed exclusions would not be eligible and would not benefit from participation.

Why it matters

Potential benefit: If successful, the robotic probe holder could streamline the injection procedure, reduce staff needs, and possibly improve injection accuracy and patient comfort.

How similar studies have performed: Direct comparisons of robot-assisted probe holding versus manual ultrasound-guided carpal tunnel injections have not been published, so this approach is largely novel in this indication.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Age ≥ 18 and ≤ 75 years.
2. Clinical diagnosis of carpal tunnel syndrome.
3. Indication for corticosteroid injection as determined by investigator.
4. Moderate to severe carpal tunnel syndrome defined by a pain score on the Visual Analogue Scale (VAS) ≥ 4 (at baseline and on day 0).
5. Signed informed consent.

Exclusion Criteria:

1. Known allergy to corticosteroids or povidone-iodine (Betadine)
2. Probable or ongoing systemic or local infection
3. History of injection in the affected wrist within the last 6 months
4. Thenar eminence atrophy
5. Trauma requiring surgery or immobilization
6. History of carpal tunnel surgery
7. Protected person (under guardianship or curatorship)
8. Person under judicial protection
9. Person deprived of liberty
10. Person not affiliated with a social security scheme
11. Pregnant or breastfeeding woman
12. Person participating in a drug trial

Where this trial is running

Orléans

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Carpal Tunnel Syndromecarpal tunnel syndromerobot-assited-ultrasonographycarpal tunnel injection
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.