Robot-assisted magnetically controlled capsule endoscopy for iron deficiency anaemia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Researchers at the University of Edinburgh will perform a single-visit procedure using a CE-marked robotic capsule system to image the upper GI tract and small intestine in adults with iron deficiency anaemia who have not had a source identified by prior tests. The aim is to see how findings from this approach compare with conventional upper GI endoscopy findings and to determine whether the robotic capsule could safely replace endoscopy in certain cases. Eligible participants are adults with confirmed iron deficiency anaemia and no previously identified cause, who would otherwise proceed to small bowel capsule endoscopy or a watch-and-wait approach. The study is conducted at Leith Community Treatment Centre in Edinburgh and involves collaboration with NHS Lothian, led by the University of Edinburgh.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult patients aged 18 and above
* Confirmed diagnosis of iron deficiency anaemia (either recent onset or recurrent)
* No significant cause for iron deficiency anaemia previously identified on upper GI endoscopy, colonoscopy or CT colonography
* Patients who would either have proceeded directly to small bowel capsule endoscopy (SBCE) or who would have had an initial 'watch and wait' period prior to undergoing SBCE

Exclusion Criteria:

* Known or suspected gastrointestinal obstruction, strictures or fistulae
* Previous abdominal surgery
* Dysphagia
* Patients with a pacemaker, defibrillator or other implanted electronic device
* In vivo retention with medical metal fittings - shunts, plates, stents or clips
* A history of metal fragments in the eyes or elsewhere in the body
* Confirmed or possible pregnancy
* Patients who are not deemed to have capacity according to the Adults with Incapacity Act
* Patients who are currently part of another research study

Where it's running

• Leith Community Treatment Centre
  Edinburgh, United Kingdom Recruiting

Study contacts

• Principal investigator: John N Plevris, MD, DM, PhD(E), FRCPE, FEBGH — University of Edinburgh
• Study coordinator: John N Plevris, MD, DM, PhD(E), FRCPE, FEBGH
• Email: j.plevris@ed.ac.uk
• Phone: 0131 242 1631

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.