Risk prediction for gastrointestinal dysfunction in colorectal cancer patients after surgery
Construction and Validation of Risk Prediction Model for Gastrointestinal Dysfunction of Patient With Colorectal Cancer After Surgery
Sun Yat-sen University · NCT05891301
This study is trying to find out which patients who have surgery for colorectal cancer are at risk for stomach and bowel problems afterward, so they can create tools to help predict these issues.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 737 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Sun Yat-sen University (other) |
| Locations | 1 site (Guangzhou, Guangdong) |
| Trial ID | NCT05891301 on ClinicalTrials.gov |
What this trial studies
This study aims to analyze postoperative gastrointestinal dysfunction in patients who have undergone radical surgery for colorectal cancer. It will identify risk factors and develop two risk prediction models, including a nomogram and a decision tree classification model. The models will be validated internally and externally to assess their clinical effectiveness and practicality. The goal is to provide a reliable tool for predicting the risk of gastrointestinal complications post-surgery.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older with diagnosed colon or rectal cancer who have undergone radical resection.
Not a fit: Patients with multiple cancers or those unable to communicate due to cognitive impairments will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could help identify patients at high risk for gastrointestinal dysfunction, allowing for targeted interventions and improved postoperative care.
How similar studies have performed: Other studies have shown success in developing risk prediction models for surgical complications, indicating that this approach has potential.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged ≥18 years; * patients with diagnosed colon or rectal cancer; * Patients diagnosed as having undergone radical resection of colorectal cancer; * Patients who can read and communicate in Chinese. Exclusion Criteria: * Patients with multiple cancers; * Patients who are unable to communicate due to dementia, language disorders or postoperative mental disorder or hearing impairment. withdrawl Criteria： * Patients with postoperative mechanical obstruction; * Patients requiring reoperation for any indication prior to the initiation of formal evaluation of POGD.
Where this trial is running
Guangzhou, Guangdong
- XIAW — Guangzhou, Guangdong, China (RECRUITING)
Study contacts
- Principal investigator: Wei Xia, Phd — Sun Yat-sun Unversity
- Study coordinator: Wei Xia, Phd
- Email: xiaw23@mail.sysu.edu.cn
- Phone: 18823359471
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Patient With Colorectal Cancer, Surgery, colorectal cancer, surgery, gastrointestinal dysfunction, risk prediction model