Risk factors and outcomes of biliary complications after adult living-donor liver transplant
Risk Factors and Outcome of Biliary Complications Following Adult Living Donor Liver Transplantation in Al-Rajhy Liver Hospital in Upper Egypt.
This project will look at how often and why bile-duct problems happen and what the outcomes are in adults who had a living-donor liver transplant at Al-Rajhy/Assiut University.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 50 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Assiut University Academic / other |
| Locations | 2 sites (Asyut and 1 other locations) |
| Trial ID | NCT03789383 on ClinicalTrials.gov |
What this trial studies
This is an observational project combining a retrospective chart review with prospective data collection from adult living-donor liver transplant recipients at Al‑Rajhy Liver Hospital, Assiut University. The team will document the frequency and specific types of biliary complications (anastomotic and non-anastomotic strictures, leaks, bilomas, stones, cholangitis, etc.) and collect perioperative and clinical variables. Analyses will seek associations between patient, donor, and surgical factors and the occurrence and clinical course of biliary complications. The study excludes pediatric and cadaveric (deceased-donor) transplants and does not introduce experimental treatments.
Who should consider this trial
Good fit: Adults aged over 18 who received a living-donor liver transplant at Al‑Rajhy Liver Hospital (Assiut University) are the intended participants.
Not a fit: Pediatric patients and recipients of cadaveric (deceased-donor) liver transplants are excluded and will not be included or directly benefit from this study's results.
Why it matters
Potential benefit: If successful, the findings could help clinicians identify modifiable risk factors and improve prevention and management of biliary complications after living-donor liver transplant.
How similar studies have performed: Previous clinical series have shown that biliary complications are common after living-donor liver transplantation and that identifying perioperative risk factors can reduce complication rates, so this work builds on established but variable evidence.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults more than 18 y with living donor liver transplantation in Al-Rajhy liver hospital , Assiut university,Egypt Exclusion Criteria: * pediatric liver transplantation * cadaveric liver transplantation
Where this trial is running
Asyut and 1 other locations
- Alrajhy center for hepatobiliary disorders — Asyut, Egypt (Recruiting)
- Al-Rajhy liver hospital — Asyut, Egypt (Not_yet_recruiting)
Study contacts
- Study coordinator: Sara Sedeek
- Email: sara_ali@aun.edu.eg
- Phone: +201022177340
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.