Clinical trial Recruiting at 1 site Observational Ages 18 and up

Right heart function and its connection to the lungs in sepsis patients seen by echocardiography

Official title: Prognostic Value of Right Ventricular-pulmonary Arterial Coupling Assessed by Echocardiography in Septic Patients: A Prospective Observational Study

Run by University Medical Center Ho Chi Minh City (UMC) · NCT06887140 · Data updated 2026-11-12

This study tests whether measuring how the right side of the heart handles blood flow against lung circulation can help understand outcomes in adults with sepsis in a hospital ICU.

More Sepsis trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment215 (estimated)
SponsorUniversity Medical Center Ho Chi Minh City (UMC)
Academic / other
Locations1 site (Ho Chi Minh City)
StatusRecruiting
StartedApril 16, 2025
Main results expectedFebruary 2027
Study endsFebruary 2027
Registry record updatedMay 27, 2026
Trial IDNCT06887140 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults with sepsis admitted to the ICU at University Medical Center Ho Chi Minh City who can undergo echocardiography.

Probably not a fit

Patients with contraindications to echocardiography or with recent acute coronary events or congenital/valvular diseases may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study evaluates right ventricular–pulmonary arterial coupling in septic patients using echocardiography. It focuses on adults treated in the ICU at University Medical Center Ho Chi Minh City and aims to relate RV function to sepsis severity and prognosis. No intervention beyond standard echocardiographic assessment is performed. The project seeks to clarify how right heart performance correlates with outcomes in sepsis and septic shock. Results could inform risk stratification and management decisions in critically ill patients.

Why it matters

Potential benefit: If successful, the study could improve understanding of prognosis in septic patients by highlighting the role of right heart function.

How similar studies have gone: Existing research has shown that right heart dysfunction occurs in sepsis and can relate to outcomes, but the specific prognostic value of right ventricular–pulmonary arterial coupling via echocardiography in this setting remains an area of ongoing study.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Diagnosed with sepsis,
* Received treatment in the Intensive Care Unit (ICU) at the University Medical Center at Ho Chi Minh City during the study period.

Exclusion Criteria:

* Pregnancy,
* History of right ventricular myocardial infarction,
* Acute coronary syndrome within the past 1 week,
* Valvular heart diseases or a history of valve replacement surgery,
* Congenital heart diseases or conditions involving intracardiac shunts.

Where it's running

  • University Medical Center
    Ho Chi Minh City, Vietnam
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.