Right heart function and its connection to the lungs in sepsis patients seen by echocardiography
Official title: Prognostic Value of Right Ventricular-pulmonary Arterial Coupling Assessed by Echocardiography in Septic Patients: A Prospective Observational Study
Run by University Medical Center Ho Chi Minh City (UMC) · NCT06887140 · Data updated 2026-11-12
This study tests whether measuring how the right side of the heart handles blood flow against lung circulation can help understand outcomes in adults with sepsis in a hospital ICU.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 215 (estimated) |
| Sponsor | University Medical Center Ho Chi Minh City (UMC) Academic / other |
| Locations | 1 site (Ho Chi Minh City) |
| Status | Recruiting |
| Started | April 16, 2025 |
| Main results expected | February 2027 |
| Study ends | February 2027 |
| Registry record updated | May 27, 2026 |
| Trial ID | NCT06887140 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults with sepsis admitted to the ICU at University Medical Center Ho Chi Minh City who can undergo echocardiography.
✕Probably not a fit
Patients with contraindications to echocardiography or with recent acute coronary events or congenital/valvular diseases may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study evaluates right ventricular–pulmonary arterial coupling in septic patients using echocardiography. It focuses on adults treated in the ICU at University Medical Center Ho Chi Minh City and aims to relate RV function to sepsis severity and prognosis. No intervention beyond standard echocardiographic assessment is performed. The project seeks to clarify how right heart performance correlates with outcomes in sepsis and septic shock. Results could inform risk stratification and management decisions in critically ill patients.
Why it matters
Potential benefit: If successful, the study could improve understanding of prognosis in septic patients by highlighting the role of right heart function.
How similar studies have gone: Existing research has shown that right heart dysfunction occurs in sepsis and can relate to outcomes, but the specific prognostic value of right ventricular–pulmonary arterial coupling via echocardiography in this setting remains an area of ongoing study.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosed with sepsis, * Received treatment in the Intensive Care Unit (ICU) at the University Medical Center at Ho Chi Minh City during the study period. Exclusion Criteria: * Pregnancy, * History of right ventricular myocardial infarction, * Acute coronary syndrome within the past 1 week, * Valvular heart diseases or a history of valve replacement surgery, * Congenital heart diseases or conditions involving intracardiac shunts.
Where it's running
-
University Medical Center
Ho Chi Minh City, Vietnam Recruiting
Study contacts
- Study coordinator: Anh-Minh V Phan, MSc.
- Email: minh.pva@umc.edu.vn
- Phone: +84907216232
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.