Clinical trial Recruiting at 1 site Interventional Ages 20 to 40

Reverse vs Sustained Natural Apophyseal Glides for Upper Cross Syndrome

Official title: Comparative Effects of Reverse Natural Apophyseal Glides Versus Sustained Natural Apophyseal Glides in Patients With Upper Cross Syndrome

Run by Foundation University Islamabad · NCT07834177 · Data updated 2026-11-12

This study tests whether two manual therapy techniques (reverse and sustained glides) added to standard physiotherapy improve posture and neck/shoulder symptoms in adults with Upper Cross Syndrome.

More Forward Head Posture trials

Quick facts

Study typeInterventional
Ages20 Years to 40 Years
SexAll
Enrollment44 (estimated)
SponsorFoundation University Islamabad
Academic / other
Locations1 site (Islamabad, Punjab Province)
StatusRecruiting
StartedFebruary 11, 2026
Main results expectedDecember 18, 2026
Study endsJanuary 18, 2027
Registry record updatedSeptember 22, 2026
Trial IDNCT07834177 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 20–40 with chronic neck pain (NPRS 3–7) and posture changes (craniovertebral angle < 48°, thoracic kyphosis > 40°) who can follow instructions and provide consent.

Probably not a fit

Individuals whose condition does not respond to cervical-thoracic manual therapy or who have exclusion criteria (e.g., cervical radiculopathy, vertebrobasilar insufficiency, recent spinal surgery, osteoporosis, pregnancy) may not experience benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults aged 20 to 40 with chronic neck pain and posture-related changes are randomized to receive either Reverse Natural Apophyseal Glides or Sustained Natural Apophyseal Glides, both in addition to a standardized physiotherapy program over four weeks. The manual therapy focuses on the lower cervical to upper thoracic spine (C6–T2), with sessions three times weekly. The protocol includes a hot pack, pectoral, upper trapezius, and levator scapulae stretching, and a strengthening program for deep neck flexors and scapular stabilizers. Outcomes will reflect changes in posture, neck pain, and functional measures. The trial is sponsored by Foundation University Islamabad with no listed collaborators and is conducted at Foundation University College of Physical Therapy in Islamabad.

Why it matters

Potential benefit: If successful, the approach could offer a more effective manual therapy option to improve posture and reduce neck pain in adults with Upper Cross Syndrome.

How similar studies have gone: Previous studies have used similar manual therapy approaches for neck-posture conditions, but direct comparison of these two glides in UCS is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria

* Both genders.
* Age 20 to 40 years.
* Patients who had been experiencing chronic neck pain for three months or longer.
* Pain intensity of 3 or more and less than 8 on NPRS.
* Craniovertebral angle less than 48 degrees.
* Thoracic kyphosis angle greater than 40 degrees
* Participants able to understand instructions and provide informed consent.

Exclusion Criteria

* Cervical radiculopathy
* Vertebrobasilar insufficiency
* Patients with a history of spinal surgery
* Any history of trauma or whiplash injury (from the past 6 months to 1 year)
* Diagnosed cases of osteoporosis
* Pregnancy
* Patients with diagnosed systemic diseases.
* Patients with a known medical diagnosis of spinal cord compression.

Where it's running

  • Foundation University College of Physical Therapy
    Islamabad, Punjab Province, Pakistan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.