Retrograde Intrarenal Surgery in Children with Kidney Stones

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study compares a minimally invasive kidney stone procedure, RIRS, in pediatric patients with stones up to 2 cm. The goal is to achieve complete stone clearance with low complication risk, balancing effectiveness and safety. Eligible children are 1–18 years old with a single or multiple stones in the kidney pelvis or calyces and normal kidney function. Exclusions include urinary tract anomalies, bleeding disorders, active infections, or anesthesia contraindications. The trial is conducted at South Valley University Hospital and is sponsored by South Valley University.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Children aged 1 to 18 years .
* Presence of a renal stone ≤2 cm in maximum diameter (single or multiple).
* Stone located in the renal pelvis and/or calyces.
* Normal renal function (based on age-adjusted serum creatinine and/or eGFR).
* No prior surgical intervention for the current stone episode.

Exclusion Criteria:

* Anatomical abnormalities of the urinary tract (e.g., ureteropelvic junction obstruction, horseshoe kidney).
* Bleeding disorders or uncorrected coagulopathy.
* Active urinary tract infection at the time of surgery.
* Patients with contraindications to general anesthesia.

Where it's running

• South Valley University Hospital
  Qina, South Valley, Egypt Recruiting

Study contacts

• Study coordinator: Mostafa Mahmoud Rashed Ali, M.D
• Email: Mostafarashed2222@gmail.com
• Phone: +20111049435

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Direct in-scope suction during flexible ureterorenoscopy for kidney and proximal ureter stones

  This study tests whether using direct in-scope suction during flexible ureterorenoscopy helps reduce infections and improve outcomes for adults with kidney or proximal ureter stones.

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• Long-term safety of UAS-assisted vs sheathless RIRS in adults with kidney stones

  This study tests whether using a ureteral access sheath during the initial RIRS affects long-term safety and outcomes in adults with kidney stones ≤20 mm.

  Recruiting Al-Azhar University · Cairo · NCT07767773

• Supervised robotic kidney stone removal with flexible ureteroscopy

  This study will test a new robotic system that lets surgeons remotely and semi-autonomously remove kidney stones during flexible ureteroscopy in adults with stones up to 2 cm.

  Recruiting at 2 sites Chinese University of Hong Kong · Hong Kong and 1 other locations · NCT07411391

• Observational study on outcomes of ECIRS for kidney stones in Asia

  This study is looking at how well a specific kidney stone surgery called ECIRS works for patients in Asia by collecting information before and after their treatment.

  Recruiting at 3 sites Chinese University of Hong Kong · Hong Kong and 2 other locations · NCT05894668

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.