Respiratory health and wellbeing after pulmonary tuberculosis
Official title: Respiratory Health and Wellbeing Post Pulmonary Tuberculosis
Run by Liverpool School of Tropical Medicine · NCT07178860 · Data updated 2026-11-12
See if people treated for pulmonary TB in the UK have ongoing lung problems and reduced wellbeing after finishing treatment.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | Liverpool School of Tropical Medicine Academic / other |
| Locations | 1 site (Liverpool) |
| Status | Recruiting |
| Started | September 1, 2025 |
| Main results expected | September 30, 2026 |
| Study ends | September 30, 2026 |
| Registry record updated | September 17, 2025 |
| Trial ID | NCT07178860 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (18 or older) in the UK with microbiologically confirmed pulmonary TB who completed TB treatment within the last 18 months and can provide informed consent.
✕Probably not a fit
People with previously diagnosed, poorly controlled chronic lung disease, those unable to perform spirometry, or those with incomplete TB treatment records may not gain useful information from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study will recruit adults in the UK who had microbiologically confirmed pulmonary TB and completed treatment within the past 18 months. Participants will undergo lung function testing (spirometry), clinical history review, and standardized questionnaires about respiratory symptoms and quality of life, with additional tests or imaging if clinically indicated. The study will describe how common and how severe post-TB respiratory and wellbeing problems are in this population and compare findings with recent international post-TB care standards. Results will inform whether routine follow-up and specific interventions are needed for TB survivors in the UK.
Why it matters
Potential benefit: If substantial post-TB problems are identified, the findings could support routine follow-up and targeted treatments to improve lung health and quality of life for TB survivors.
How similar studies have gone: Multiple studies from low- and middle-income countries have shown high rates of post-TB lung impairment and international guidance has been published, but comparable UK data are limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * 1\) Adults (over 18 years old) 2) Able to provide written informed consent 3) Previous diagnosis of microbiologically confirmed pulmonary TB 4) Completed TB treatment less than or equal to 18 months ago Exclusion Criteria: * 1\) Previously diagnosed clinically significant chronic lung disease that is not well-controlled (for example COPD on significant treatment, or poorly controlled asthma) 2) Unable to perform spirometry due to contraindications to spirometry 3) Under the age of 18 years at the time of recruitment (not the time of initial diagnosis) 4) Incomplete history of TB treatment
Where it's running
-
Liverpool School of Tropical Medicine
Liverpool, United Kingdom Recruiting
Study contacts
- Study coordinator: Rebecca Nightingale, PhD
- Email: rebecca.nightingale@lstmed.ac.uk
- Phone: 07702812183
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.