Resource and biobank for chronic kidney disease research
Clinical Phenotyping Resource and Biobank Core of the Michigan O'Brien Renal Center
This study is collecting samples and information from people with chronic kidney disease to help researchers find new ways to understand and treat the condition.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1800 (estimated) |
| Sex | All |
| Sponsor | University of Michigan Academic / other |
| Locations | 5 sites (Ann Arbor, Michigan and 4 other locations) |
| Trial ID | NCT01016613 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on chronic kidney disease (CKD) and glomerulopathy, aiming to create a biobank and resource for researchers. It seeks to characterize tissue profiles to identify new disease markers and molecular pathways associated with CKD. By gathering data from individuals with CKD and a small number of healthy participants, the study aims to enhance understanding of the disease and facilitate future research. The findings will be made available to kidney investigators to promote advancements in CKD prevention and treatment.
Who should consider this trial
Good fit: Ideal candidates include individuals of any age with chronic kidney disease or a small number of healthy individuals for comparison.
Not a fit: Patients on dialysis, those who have had a kidney transplant, or individuals with polycystic kidney disease may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to the identification of new biomarkers and therapeutic targets for chronic kidney disease.
How similar studies have performed: Other studies focusing on CKD and biobanking have shown promise in advancing understanding and treatment options, indicating that this approach is both relevant and potentially impactful.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * persons of any age who have chronic kidney disease (abnormally high protein in urine or reduced kidney function determined by blood tests) * a small number of people without chronic kidney disease Exclusion Criteria: * people on hemodialysis or peritoneal dialysis * people who have had a kidney transplant * people unable or unwilling to provide consent * women who are pregnant or nursing * adults who have polycystic kidney disease * institutionalized persons * people currently participating in a blinded interventional clinical trial
Where this trial is running
Ann Arbor, Michigan and 4 other locations
- University of Michigan Health System — Ann Arbor, Michigan, United States (Recruiting)
- Wayne State University — Detroit, Michigan, United States (Completed)
- St. John's Health System — Detroit, Michigan, United States (Completed)
- Levine Children's Hospital — Charlotte, North Carolina, United States (Completed)
- Temple University — Philadelphia, Pennsylvania, United States (Completed)
Study contacts
- Principal investigator: Subramanium Pennathur, MBBS — University of Michigan
- Study coordinator: Chrysta Lienczewski
- Email: boridley@med.umich.edu
- Phone: 734-615-5021
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.