Research on treating blocked coronary arteries in Taiwan
Official title: The Multicenter Study to Evaluate Clinical and Angiographic Factors in Patients With Coronary Artery Chronic Total Occlusion in Taiwan
Run by National Taiwan University Hospital · NCT06917378 · Data updated 2026-11-12
This study looks at different ways to treat blocked coronary arteries to see how well they work for people with chronic total occlusions.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 20 Years to 120 Years |
| Sex | All |
| Enrollment | 5000 (estimated) |
| Sponsor | National Taiwan University Hospital Academic / other |
| Locations | 3 sites (New Taipei City and 2 other locations) |
| Status | Recruiting |
| Started | January 15, 2015 |
| Main results expected | December 31, 2034 |
| Study ends | December 31, 2034 |
| Registry record updated | October 16, 2026 |
| Trial ID | NCT06917378 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals over 20 years old with a confirmed chronic total occlusion lasting more than three months.
✕Probably not a fit
Patients with acute coronary occlusions or those under 20 years old may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to create a multicenter cohort to evaluate the clinical parameters, angiographic characteristics, interventional techniques, and outcomes of coronary interventions for chronic total occlusions (CTO). It includes three subprojects focusing on optimizing intervention algorithms, examining strategies for bifurcation CTO lesions, and investigating treatment strategies for right coronary artery CTOs with concomitant left main disease. The study will utilize data from multiple hospitals to enhance understanding and improve treatment approaches for CTOs.
Why it matters
Potential benefit: If successful, this study could lead to improved strategies for treating chronic total occlusions, potentially enhancing patient outcomes in interventional cardiology.
How similar studies have gone: Other studies have shown success in similar approaches to treating coronary total occlusions, indicating a promising avenue for further exploration.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion criteria 1. Over 20 years old 2. Chronic total occlusion confirmed by coronary angiography, and noted for more than 3 months Exclusion criteria Nil
Where it's running
-
Chang Gung Memorial Hospital
New Taipei City, Taiwan Recruiting -
National Taiwan University Hospital
Taipei, Taiwan Recruiting -
Taipei Veterans General Hospital
Taipei, Taiwan Recruiting
Study contacts
- Principal investigator: Hsien-Li Kao, MD — National Taiwan University Hospital
- Study coordinator: Chih Fan Yeh
- Email: nicholas.yeh@gmail.com
- Phone: +8862-23123456
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Drug-coated balloons versus drug-eluting stents for chronic total occlusion of coronary arteries
This will test whether using drug-coated balloons (alone or with a stent when needed) works as well as drug-eluting stents alone for people whose chronically blocked coronary artery has been successfully opened.
-
Using intracoronary imaging more often to improve outcomes of complex coronary stenting
This project tests whether more frequent use of intracoronary imaging during complex stenting procedures for adults with complicated coronary artery disease leads to better stent results and fewer major complications.
-
FAPI PET/CT to predict adverse cardiac events after PCI for chronic total occlusion
This will test whether FAPI PET/CT scans done before PCI can help predict major heart problems within 12 months in adults with chronic total coronary occlusion.
-
Using a new guidewire system to treat blocked coronary arteries
This study is testing a new guidewire system to see if it can help doctors treat blocked coronary arteries in patients who have had these blockages for over three months.
-
Comparing heart procedures and medication for blocked coronary arteries
This study is testing if a heart procedure called PCI can help people with completely blocked coronary arteries feel better and have improved heart function compared to just using medication.
-
Comparing two approaches for treating blocked coronary arteries
This study is testing two different methods for treating blocked coronary arteries to see which one works better and is safer for patients with chronic total occlusions.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.