Research on primary aldosteronism and its effects on hypertension

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to establish a large cohort of patients with primary aldosteronism (PA) and essential hypertension, focusing on long-term follow-up of cardiovascular and renal outcomes. It will collect extensive biological samples, including blood, urine, and adrenal tissue, to create a comprehensive database for genomics, metabonomics, and proteomics analysis. The goal is to explore the mechanisms behind PA, identify risk factors, and develop diagnostic methods and biomarkers for better management of the condition.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. hypertensive patients who completed ARR screening and necessary further tests;
2. Voluntary to sign the informed consent.

Exclusion Criteria:

1. patients with severe cardiac, hepatic or renal dysfunction;
2. suspicious or confirmed other types of secondary hypertension, including Cushing's syndrome, pheochromocytoma and renal artery stenosis et al.

Where it's running

• Qifu Li
  Chongqing, Chongqing Municipality, China Recruiting

Study contacts

• Study coordinator: Qifu Li, phD
• Email: liqifu@yeah.net
• Phone: +86 023-89011552

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Kidney stiffness measured by ultrasound in hypertension and healthy volunteers

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• Inclisiran vs. Statin for Primary Aldosteronism

  This trial tests whether inclisiran plus amlodipine works differently from a statin-based approach in people with primary aldosteronism and high blood pressure.

  Recruiting Third Military Medical University · Chongqing, Chongqing Municipality · NCT07884955

• Left-atrial Fibrosis in Persistent Atrial Fibrillation and Its Comorbidities

  This study tests how comorbid conditions like sleep apnea and primary aldosteronism relate to left-atrial fibrosis and AF recurrence in patients undergoing ablation.

  Recruiting University Hospital Augsburg · Augsburg, Bavaria · NCT07857044

• Metomidate PET-CT vs Usual Care for Primary Aldosteronism

  This study tests whether [11C] metomidate PET-CT can help orient treatment for people with primary aldosteronism compared with the usual adrenal venous sampling approach.

  Recruiting Chinese University of Hong Kong · Shatin · NCT07814105

• Captopril Test with LC-MS/MS for Aldosterone and Renin in Primary Aldosteronism

  This study tests whether measuring aldosterone with LC-MS/MS during a captopril test can better diagnose primary aldosteronism.

  Recruiting Peking Union Medical College Hospital · Beijing, Beijing Municipality · NCT07691801

• Finerenone vs. Spironolactone for Primary Aldosteronism

  This trial tests whether finerenone works as well as spironolactone to lower blood pressure and improve related health measures in adults with primary aldosteronism.

  Recruiting Bangladesh Medical University · Dhaka · NCT07688928

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.