Research on genetic causes of brain development disorders

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This research program at the University of California, San Francisco focuses on understanding the genetic factors contributing to brain disorders, particularly those affecting the corpus callosum, such as Aicardi syndrome, polymicrogyria, and Dandy-Walker malformation. The study involves collecting MRI scans, clinical information, and biological samples from affected individuals and their parents to explore the clinical features and underlying genetic causes of these conditions. The ultimate goal is to develop targeted therapies based on the biological insights gained from this research.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Clinical diagnosis of agenesis or dysgenesis of the corpus callosum, polymicrogyria, or Dandy-Walker malformation
* Should be confirmed by an MRI (Magnetic Resonance Imaging) of the brain

Exclusion Criteria:

* Fully formed but hypoplastic corpus callosum

Where it's running

• University of California, San francisco
  San Francisco, California, United States Recruiting

Study contacts

• Principal investigator: Elliott H Sherr, MD, PhD — University of California, San Francisco
• Study coordinator: Carolyn Le, BA, BS
• Email: Carolyn.Le@ucsf.edu
• Phone: 415-502-8039

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.