Research on diagnosing vascular dementia in stroke patients
Research on the Early and Prognosis Diagnosis of Vascular Dementia
This study is testing if certain markers in the blood can help doctors spot and understand vascular dementia earlier in stroke patients.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 600 (estimated) |
| Ages | 65 Years and up |
| Sex | All |
| Sponsor | National Taiwan University Hospital Academic / other |
| Locations | 1 site (Taipei) |
| Trial ID | NCT03152630 on ClinicalTrials.gov |
What this trial studies
This observational study aims to identify novel biomarkers for early diagnosis and prognosis of vascular dementia in stroke patients. It focuses on the role of long non-coding RNAs (lncRNAs) in cognitive dysfunction following a stroke. By analyzing the expression of lncRNAs, the study seeks to provide insights into the pathogenesis of dementia and improve clinical care tailored to individual risk profiles. The ultimate goal is to enhance therapeutic strategies for patients at risk of developing dementia after a stroke.
Who should consider this trial
Good fit: Ideal candidates for this study are stroke survivors over the age of 20 with a history of atherosclerotic vascular diseases and at least one cardiovascular risk factor.
Not a fit: Patients who do not have a history of stroke or those unwilling to participate in the study will not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier and more accurate diagnoses of vascular dementia, improving patient outcomes.
How similar studies have performed: While the role of lncRNAs in other diseases is emerging, this specific approach to vascular dementia in stroke patients is relatively novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * age older than 20 years old * willing to sign ICF * report oneself disease * have Taiwanese ID * atherosclerotic vascular diseases, but with at least 1 CV risk factor \[DM, dyslipidemia or under lipid lowering therapy, hypertension, smoking, old (M\>45, F\>55 years), family history of premature CAD, obesity Exclusion Criteria: * not willing to sign ICF
Where this trial is running
Taipei
- Ntuh — Taipei, Taiwan (Recruiting)
Study contacts
- Principal investigator: Chau C Wu, M.D., Ph.D. — National Taiwan University Hospital
- Study coordinator: Chau C Wu, M.D., Ph.D.
- Email: chauchungwu@ntu.edu.tw
- Phone: 886-2-23123456
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.