Research on carotid plaques and their imaging
Carotid Plaque Imaging Project (Identification of Vulnerable Atherosclerotic Plaques With Imaging and Biological Markers)
This study is trying to find out how to spot dangerous plaques in the arteries that could cause heart attacks or strokes by looking at samples removed during surgery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 3500 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Lund University Academic / other |
| Locations | 1 site (Malmö, Skåne County) |
| Trial ID | NCT05821894 on ClinicalTrials.gov |
What this trial studies
This project focuses on understanding atherosclerotic plaques that can lead to heart attacks and strokes by studying plaques removed during carotid endarterectomy. The researchers aim to identify vulnerable plaques through advanced imaging techniques and circulating biomarkers, which may help in early detection and treatment. By analyzing the structure and mechanisms of these plaques, the study seeks to uncover potential therapeutic targets or markers for better management of atherosclerosis.
Who should consider this trial
Good fit: Ideal candidates are adults over 18 years old who are eligible for carotid endarterectomy due to atherosclerosis.
Not a fit: Patients under 18 years old or those who cannot provide informed consent will not benefit from this study.
Why it matters
Potential benefit: If successful, this research could lead to improved early detection and treatment strategies for patients at risk of cardiovascular events.
How similar studies have performed: Other studies have explored similar imaging techniques for atherosclerosis, indicating potential for success in this area.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients older than 18 years old, male or female that are eligible for carotid endarterectomy due to atherosclerosis and that can provide informed consent. Exclusion Criteria: * Patients younger than 18 years old that cannot provide informed consent; pregnant.
Where this trial is running
Malmö, Skåne County
- Skåne University Hospital (SUS) — Malmö, Skåne County, Sweden (Recruiting)
Study contacts
- Principal investigator: Isabel Goncalves, MD, PhD — Lund University
- Study coordinator: Isabel Goncalves, MD, PhD
- Email: Isabel.Goncalves@med.lu.se
- Phone: +46 40 331000
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.