Replacing sugary sodas with flavored sparkling water for Black/African American and Latine teens with obesity

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized, three-arm intervention enrolls 63 adolescents aged 12–18 who self-identify as Black/African American or Latine, have obesity (BMI >95th percentile), and show a "sweet-liker" pattern. Participants are randomized to replace their usual sugary sodas for 4 weeks with either unsweetened flavored sparkling water, progressively reduced-sugar beverages, or plain water, followed by a 4-week follow-up. Outcomes include repeated sensory testing of beverage liking and sweetness perception, 24-hour dietary recalls, anthropometrics, blood pressure, and blood biomarkers measured at baseline, week 2, week 4, and week 8. The trial compares which beverage-replacement strategy best reduces added sugar intake and improves diet quality and cardiometabolic indicators.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adolescents ages 12 to 18 who display a "sweet-liker" pattern, characterized by a preference for higher concentrations of sugar in beverages, specifically identifying 0.3M (10.3% sucrose) or above as their most liked sample.
* Adolescents consumes sugar-sweetened soda greater than or equal to 2 times per week. Adolescents must also indicate a willingness to drink study beverages; not currently dieting/changing diet.

Exclusion Criteria:

* Adolescent participant is pregnant, since pregnancy affects taste perception
* Participant is allergic or intolerant to the items we are testing.
* Adolescent with type 1 or type 2 diabetes (self-declared or detected at screening visit through fasting glucose)
* Use of GLP-1 receptor agonists intended for weight loss.

Where it's running

• Indiana University Hospital
  Indianapolis, Indiana, United States Recruiting
• Purdue University
  West Lafayette, Indiana, United States Recruiting
• Indiana University School of Public Health - Bloomington
  Bloomington, Indiana, United States Not yet recruiting

Study contacts

• Study coordinator: Nana Gletsu Miller, PhD
• Email: ngletsum@iu.edu
• Phone: +1 (812) 855-9110

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.