Clinical trial Recruiting at 1 site Interventional

Repeatability of the combined exercise and heart ultrasound test (CPETecho)

Official title: Analysing the Test-Retest Reliability of Cardiopulmonary Exercise Testing With Echocardiography

Run by Ziekenhuis Oost-Limburg · NCT07281534 · Data updated 2026-11-12

We will test whether repeating the combined exercise and heart ultrasound test gives consistent results in people with breathlessness or heart conditions who can complete a maximal exercise test.

More Dyspnea trials

Quick facts

Study typeInterventional
SexAll
Enrollment30 (estimated)
SponsorZiekenhuis Oost-Limburg
Academic / other
Locations1 site (Genk)
StatusRecruiting
StartedNovember 1, 2025
Main results expectedMarch 1, 2026
Study endsJune 1, 2026
Registry record updatedDecember 15, 2025
Trial IDNCT07281534 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults with dyspnea or cardiac conditions who can safely perform a maximal exercise test, can delay urgent therapy for about a week, and can give informed consent are ideal candidates.

Probably not a fit

Patients with unstable symptoms who cannot postpone treatment, those unable to complete maximal exercise testing, or those unable to attend in-person visits are unlikely to benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Cardiopulmonary exercise testing with echocardiography (CPETecho) combines maximal exercise testing with non-invasive heart ultrasound to measure cardiac and pulmonary responses. Participants will perform a maximal CPETecho session and then repeat the test about one week later to determine test-retest reliability. This protocol replaces invasive hemodynamic catheter monitoring with echocardiography during exercise to capture cardiac function. Data collected at Ziekenhuis Oost-Limburg (Genk) will quantify measurement variability and help distinguish true physiological change from measurement noise.

Why it matters

Potential benefit: If reliable, CPETecho could provide a non-invasive, repeatable way to monitor cardiac and pulmonary function during exercise and reduce the need for invasive catheter testing.

How similar studies have gone: Invasive cardiopulmonary exercise testing with catheter monitoring is well-established, but non-invasive CPETecho is an evolving approach with limited published data on test-retest reliability.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Capable of performing a maximal exercise test.
* Provide signed and dated informed consent.

Exclusion Criteria:

\- Unstable symptoms, whereby therapy cannot be delayed for a week.

Where it's running

  • Ziekenhuis Oost-Limburg
    Genk, Belgium
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.