Clinical trial Recruiting at 1 site Interventional Ages 20 to 40

Removal of Intracanal Medicaments Using Different Techniques

Official title: "Removal of Intracanal Medicament by Different Techniques: (Cone Beam Computed Tomography Analysis) (Clinical Study)"

Run by Tanta University · NCT07719985 · Data updated 2026-11-12

This study tests which activation technique best removes intracanal medication from a single mature, non-vital anterior tooth using cone beam CT to measure cleanliness.

Quick facts

Study typeInterventional
Ages20 Years to 40 Years
SexAll
Enrollment30 (estimated)
SponsorTanta University
Academic / other
Locations2 sites (Tanta, Gharbia Governorate and 1 other locations)
StatusRecruiting
StartedAugust 4, 2026
Main results expectedFebruary 2027
Study endsMarch 2027
Registry record updatedOctober 6, 2026
Trial IDNCT07719985 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults with restorable, mature, non-vital single-canal anterior teeth and no systemic health issues.

Probably not a fit

Patients with multi-canal or structurally compromised teeth, retreatment cases, or root fractures may not benefit from the findings.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The trial compares manual dynamic agitation, sonic activation, and XP-Endo Finisher activation to remove calcium hydroxide medication from the root canal. Cone beam computed tomography analysis is used to quantify the amount of medicament remaining after each technique. Participants are medically healthy adults with restorable, non-vital, single-canal anterior teeth, without anatomical variations. The study aims to identify which technique most effectively debrides the canal to improve treatment outcomes. The investigational focus is on optimizing chemo-mechanical disinfection during endodontic retreatment scenarios.

Why it matters

Potential benefit: If successful, patients could experience more thorough removal of intracanal medicament, potentially improving healing and reducing persistent infection.

How similar studies have gone: Previous endodontic studies show that activation techniques can influence medicament removal, but direct CT-based comparisons of these three methods are not yet well established.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Restorable mature non-vital single canal anterior tooth with or without signs of periapical pathosis.
2. Teeth without anatomical variations
3. Medically free patients

Exclusion Criteria:

1. Non-restorable tooth
2. Retreatment cases
3. Teeth with root fractures
4. Teeth with root resorption

Where it's running

  • Tanta University, Faculty of Dentistry
    Tanta, Gharbia Governorate, Egypt
    Recruiting
  • Faculty of Dentistry, Tanta University
    Tanta, Gharbia Governorate, Egypt
    Not yet recruiting

Study contacts

  • Principal investigator: Ahmed H Labib, professor of endodontics — Faculty of Dentistry, Tanta University
  • Study coordinator: Mahmoud B Basuoni Aboseira, BDS
  • Email: PG_191164@dent.tanta.edu.eg
  • Phone: +21019469738

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.