Removal of Intracanal Medicaments Using Different Techniques
Official title: "Removal of Intracanal Medicament by Different Techniques: (Cone Beam Computed Tomography Analysis) (Clinical Study)"
Run by Tanta University · NCT07719985 · Data updated 2026-11-12
This study tests which activation technique best removes intracanal medication from a single mature, non-vital anterior tooth using cone beam CT to measure cleanliness.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 20 Years to 40 Years |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | Tanta University Academic / other |
| Locations | 2 sites (Tanta, Gharbia Governorate and 1 other locations) |
| Status | Recruiting |
| Started | August 4, 2026 |
| Main results expected | February 2027 |
| Study ends | March 2027 |
| Registry record updated | October 6, 2026 |
| Trial ID | NCT07719985 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults with restorable, mature, non-vital single-canal anterior teeth and no systemic health issues.
✕Probably not a fit
Patients with multi-canal or structurally compromised teeth, retreatment cases, or root fractures may not benefit from the findings.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The trial compares manual dynamic agitation, sonic activation, and XP-Endo Finisher activation to remove calcium hydroxide medication from the root canal. Cone beam computed tomography analysis is used to quantify the amount of medicament remaining after each technique. Participants are medically healthy adults with restorable, non-vital, single-canal anterior teeth, without anatomical variations. The study aims to identify which technique most effectively debrides the canal to improve treatment outcomes. The investigational focus is on optimizing chemo-mechanical disinfection during endodontic retreatment scenarios.
Why it matters
Potential benefit: If successful, patients could experience more thorough removal of intracanal medicament, potentially improving healing and reducing persistent infection.
How similar studies have gone: Previous endodontic studies show that activation techniques can influence medicament removal, but direct CT-based comparisons of these three methods are not yet well established.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Restorable mature non-vital single canal anterior tooth with or without signs of periapical pathosis. 2. Teeth without anatomical variations 3. Medically free patients Exclusion Criteria: 1. Non-restorable tooth 2. Retreatment cases 3. Teeth with root fractures 4. Teeth with root resorption
Where it's running
-
Tanta University, Faculty of Dentistry
Tanta, Gharbia Governorate, Egypt Recruiting -
Faculty of Dentistry, Tanta University
Tanta, Gharbia Governorate, Egypt Not yet recruiting
Study contacts
- Principal investigator: Ahmed H Labib, professor of endodontics — Faculty of Dentistry, Tanta University
- Study coordinator: Mahmoud B Basuoni Aboseira, BDS
- Email: PG_191164@dent.tanta.edu.eg
- Phone: +21019469738
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.