Remote home rehabilitation improves quality of life in pulmonary hypertension patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effectiveness of mobile Internet-based remote home rehabilitation for patients with pulmonary hypertension. Participants will engage in tele-rehabilitation training, which includes impedance training, under the guidance of a rehabilitation trainer and psychotherapist during their hospital stay. The study compares the outcomes of the tele-rehabilitation group with a control group receiving health education and following their usual routine post-discharge. The primary focus is to assess improvements in prognostic function and quality of life.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 1\. age 18- 60 years old;
* 2\. PH were defined as: mPAP \> 20 mmHg, PAWP ≦ 15 mmHg and PVR \> 2 WU measured by right heart catheterization at sea level at rest;
* 3\. Arterial Pulmonary Hypertension (PAH), pulmonary hypertension associated with lung diseaseor and Chronic Thromboembolic Pulmonary Hypertension (CTEPH) according to the WHO PH Classification;
* 4\. no syncope or syncopal aura during walking or recovery.
* 5\. no serious arrhythmia caused by rest or exercise such as ventricular tachycardia, ventricular fibrillation, Class III atrioventricular block, etc.
* 6\. stable medication and medication regimen for at least 3 months prior to randomization and no organized exercise training of any kind for at least 3 months prior to screening
* 7\. be proficient in the use of smartphones and monitoring devices;
* 8\. sign an informed consent form.

Exclusion Criteria:

* 1\. combined with VTE.
* 2\. acute pulmonary embolism.
* 3\. low-intensity exercise (\<3METs) or angina pectoris symptoms/signs during the recovery period.
* 4\. hemodynamic abnormality during exercise (especially systolic blood pressure doesn't rise or fall or arrhythmia occurs when the exercise load is increased).
* 5\. severe psycho-cognitive disorders.
* 6\. couldent do exercise due to the neurological or musculoskeletal dysfunction.
* 7\. patients with CTEPH who are scheduled to undergo percutaneous pulmonary artery balloon dilatation or pulmonary artery endarterectomy within 6 months.
* 8\. patients with a combination of other consumptive underlying diseases, such as malignant tumors, pulmonary tuberculosis, hyperthyroidism, severe depression, etc.
* 9\. pregnancy.
* 10\. refused to sign the informed consent form.

Where it's running

• Fuwai Hospital
  Beijing, Beijing Municipality, China Recruiting

Study contacts

• Study coordinator: Xiaoming Zhou, MD
• Email: zhouxmcmu@163.com
• Phone: +86 88396992

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.