Rehabilitation training for orthostatic hypotension in Parkinson's patients
The Effect of Rehabilitation Training on Orthostatic Hypotension in Parkinson's Patients: a Randomized Controlled Trial
This study is testing if a special bed training can help people with Parkinson's disease who have low blood pressure when they stand up feel better.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 80 (estimated) |
| Ages | 40 Years and up |
| Sex | All |
| Sponsor | People's Hospital of Zhengzhou University Academic / other |
| Locations | 1 site (Xinzhu) |
| Trial ID | NCT06255717 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the effects of raise-bed training on orthostatic hypotension in patients with Parkinson's disease. Participants will be randomly assigned to either a control group or an experimental group receiving raise-bed training, alongside comprehensive rehabilitation treatment. The study will last for 21 days, during which researchers will evaluate changes in symptoms using various scales, including the Orthostatic Hypotension Questionnaire and the Composite Autonomic Symptom Scale 31. The aim is to determine if this specific training can alleviate symptoms of orthostatic hypotension.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 40 and older with a confirmed diagnosis of Parkinson's disease and orthostatic hypotension.
Not a fit: Patients with severe cardiovascular diseases or those unable to participate in the required rehabilitation training may not benefit from this study.
Why it matters
Potential benefit: If successful, this intervention could significantly improve the management of orthostatic hypotension in Parkinson's patients, enhancing their quality of life.
How similar studies have performed: While there is limited data on raise-bed training specifically, similar rehabilitation approaches have shown promise in managing orthostatic hypotension in other patient populations.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Confirmed diagnosis of Parkinson's disease * Presence of orthostatic hypotension, defined as a decrease in systolic blood pressure of at least 20 mmHg or a decrease in diastolic blood pressure of at least 10 mmHg within three minutes of standing up * Age 40 years or older * Willingness to participate in the study and provide informed consent Exclusion Criteria: * Severe cardiovascular disease or other medical conditions that would make head-up tilt treatment unsafe or inappropriate * Use of medications that affect blood pressure or heart rate, such as beta-blockers or vasodilators, and inability or unwillingness to discontinue these medications for the study period * History of syncope or falls within the past six months * Inability to stand or sit up independently or tolerate changes in body position * Cognitive impairment or inability to provide informed consent
Where this trial is running
Xinzhu
- Gaoxiong Rehabilitation Hospital — Xinzhu, Taiwan (Recruiting)
Study contacts
- Study coordinator: Qianyun Lu, Master
- Email: 535226944@qq.com
- Phone: 15333866454
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.