Rehabilitation programs for cognitive impairment in older adults
Comparing the Effectiveness of Multidimensional Rehabilitation Programs for Cognitive Impairment in Comorbid Outpatients: a Randomized Controlled Trial
This study is testing if a combined program of physical and mental exercises can help older adults with cognitive problems from vascular diseases improve their thinking skills and overall health.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 75 (estimated) |
| Ages | 65 Years to 80 Years |
| Sex | All |
| Sponsor | Istituti Clinici Scientifici Maugeri SpA Academic / other |
| Locations | 1 site (Montescano, Pavia) |
| Trial ID | NCT05954741 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the effectiveness of multidimensional rehabilitation programs that combine motor and cognitive training for older adults suffering from cognitive impairment due to vascular diseases. Participants aged 65 to 80 with specific neurocognitive disorders will be randomized to receive either motor rehabilitation alone or combined motor and cognitive rehabilitation through paper-based or digital methods. The study aims to clarify the efficacy of these interventions in improving cognitive functions and overall health in patients with comorbid conditions. By utilizing both physical and cognitive rehabilitation strategies, the trial seeks to enhance patient-centered care and outcomes.
Who should consider this trial
Good fit: Ideal candidates are older adults aged 65 to 80 with neurocognitive disorders due to vascular disease and a Clinical Dementia Rating Scale score between 0.5 and 1.
Not a fit: Patients with other neurological conditions, severe psychiatric issues, or significant motor disabilities may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved cognitive functioning and quality of life for elderly patients with vascular dementia and comorbidities.
How similar studies have performed: Preliminary evidence suggests that similar multidimensional rehabilitation approaches have shown promise, but this specific combination is still being tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age Between 65 and 80 years. * Neurocognitive Disorder due to vascular disease with Clinical Dementia Rating Scale score between 0.5 and 1, symptoms onset \< 12 months. * Neurocognitive Disorder due to multiple etiology with Clinical Dementia Rating Scale score between 0.5 and 1, symptoms onset \< 12 months. Exclusion Criteria: * Other known neurological conditions involving cognitive functioning (e.g. Parkinson's disease, Multiple Sclerosis, head trauma, alcohol abuse). * Severe organic instability. * Neoplasia in progress. * Severe psychiatric condition. * Illiteracy. * Severe perception deficits. * Severe motor disability. * Specific intellectual deficit. * Participation in other forms of training or neurostimulation in the previous 6 months. * Pharmacological interventions of neurological pertinence in the month before the study.
Where this trial is running
Montescano, Pavia
- ICS Maugeri - Montescano — Montescano, Pavia, Italy (Recruiting)
Study contacts
- Study coordinator: Cira Fundarò, MD
- Email: cira.fundaro@icsmaugeri.it
- Phone: +39 0385247268
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.