Rehabilitation program for allogeneic bone marrow transplant patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a pragmatic, two-arm randomized controlled trial comparing the CaRE-4-alloBMT rehabilitation program to usual care in adults undergoing allogeneic bone marrow transplant. Participants complete questionnaires and an initial assessment with a registered kinesiologist, then are randomized to the intervention or usual care. Outcomes include patient-reported measures and physiological assessments collected at baseline, hospital admission, discharge, and at 3 and 6 months post-discharge to capture real-world recovery. The trial emphasizes external validity to inform whether the program can be delivered in routine clinical practice.

Why it matters

Who can join: the full rules

Inclusion Criteria:

• scheduled to undergo alloBMT and are:

* \> 18 years of age;
* receiving treatment for a hematologic cancer;
* completing pre- and post-transplant care at PM;
* able to access on-line study material; and
* able to understand (spoken and written) English. Participants receiving a second transplant at the time of screening will be included if they meet the above criteria.

Exclusion Criteria:

* scheduled to be admitted to the hospital for their alloBMT \< 2 weeks from the initial assessment booking, as this will not allow enough time for the prehabilitation phase of the study;
* are participating in any other clinical trials or supportive care intervention studies; or
* have comorbidities or musculoskeletal complications that preclude participation in the exercise programs.

Where it's running

• Princess Margaret Cancer Centre
  Toronto, Ontario, Canada Recruiting

Study contacts

• Principal investigator: Jennifer M Jones, PhD — UHN Princess Margaret Cancer Centre
• Study coordinator: Jennifer M Jones, PhD
• Email: Jennifer.jones@uhn.ca
• Phone: 14165818603

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.