Clinical trial Recruiting at 1 site Observational Ages 18 to 110

Rehabilitation for patients recovering from cardiogenic shock

Official title: A framEwork for aN InteGrated assessMent of cArdiac Rehabilitation Programs in Patients Acutely Managed for Cardiogenic Shock - ENIGMA-shock

Run by Fondazione Don Carlo Gnocchi ETS · NCT06572826 · Data updated 2026-11-12

This study is testing how well cardiac rehabilitation helps people recover and improve their quality of life after experiencing cardiogenic shock.

More Cardiogenic Shock trials

Quick facts

Study typeObservational
Ages18 Years to 110 Years
SexAll
Enrollment2000 (estimated)
SponsorFondazione Don Carlo Gnocchi ETS
Academic / other
Locations1 site (Milan)
StatusRecruiting
StartedAugust 31, 2024
Main results expectedOctober 30, 2026
Study endsJanuary 31, 2027
Registry record updatedSeptember 2, 2026
Trial IDNCT06572826 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients with a clinical diagnosis of cardiogenic shock who are willing to provide informed consent.

Probably not a fit

Patients who refuse to give informed consent will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess the outcomes of cardiac rehabilitation in patients who have been acutely managed for cardiogenic shock. Utilizing the Altshock registry, the largest multicenter registry for cardiogenic shock in Italy, the study will evaluate post-acute care programs, focusing on functional recovery, quality of life, and economic efficiency. It will include a cohort of approximately 2000 patients, analyzing survival rates and recovery metrics over 6 months and 1 year post-ICU discharge. The study employs a mixed-method approach to validate an innovative care model compared to traditional pathways.

Why it matters

Potential benefit: If successful, this study could improve recovery outcomes and quality of life for patients who have experienced cardiogenic shock.

How similar studies have gone: Other studies have shown promising results in cardiac rehabilitation for similar conditions, indicating potential for success in this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

• All consecutive patients with a clinical diagnosis of Cardiogenic Shock.

Exclusion Criteria:

• Refusal to give informed consent.

Where it's running

  • Fondazione Don Gnocchi
    Milan, Italy
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.