Rehabilitation combining language and metacognitive training for chronic vascular aphasia
Effect of Anomia Rehabilitation Combined With Metacognitive Training in Patients With Chronic Vascular Aphasia
This study is testing a new rehab program that combines language and thinking skills training to see if it helps people with chronic vascular aphasia improve their communication after a stroke.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 18 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University Hospital, Toulouse Academic / other |
| Locations | 1 site (Toulouse) |
| Trial ID | NCT06930131 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effects of a combined rehabilitation approach that integrates linguistic and metacognitive training for patients with chronic vascular aphasia following a stroke. It aims to improve language performance and enhance functional cerebral connectivity networks, potentially benefiting both verbal and non-verbal communication skills. The study is a prospective, randomized controlled, open-label, single-centre trial conducted at the University Hospital of Toulouse. Participants will undergo semantic rehabilitation to address word-finding difficulties associated with aphasia.
Who should consider this trial
Good fit: Ideal candidates are individuals who have experienced their first cerebral infarction and are in the chronic phase of recovery, with mild to moderate aphasia.
Not a fit: Patients with pre-existing cognitive impairments, severe psychiatric conditions, or those unable to undergo MRI may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly enhance communication abilities and overall quality of life for patients with chronic vascular aphasia.
How similar studies have performed: While studies have explored linguistic and metacognitive training separately, this combined approach is novel and has not been previously assessed in post-stroke aphasic patients.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * First cerebral infarction * Chronic phase (\> 3 months) * Patient affiliated to a health insurance scheme * Usual french language * Severity score measures using the Boston Diagnostic Aphasia Examination battery scale corresponding to the mild or moderate level (score greater than or equal to 2) Exclusion Criteria: * Contraindication to undergoing brain MRI * Cognitive impairment pre-existing stroke (CQI code \> 3.4) (Law et al., 1995) * Chronic alcohol or drug abuse * Unstabilised psychiatric illness * Uncorrected sensory deficits * Diagnosed as having a progressive general pathology
Where this trial is running
Toulouse
- University Hospital of Toulouse — Toulouse, France (Recruiting)
Study contacts
- Study coordinator: Lola DANET
- Email: danet.l@chu-toulouse.fr
- Phone: 05 61 77 76 86
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.