Rehabilitation after heart valve surgery

"Postoperative Mobilization and Bottle-P.E.P. in Heart Valve Surgery:A Prospective Randomized Controlled Study "

Not applicable Interventional Istanbul Saglik Bilimleri University · NCT06493123

This study is testing if early movement and a special breathing device can help people recover better after heart valve surgery compared to standard rehab.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment60 (estimated)
Ages25 Years to 75 Years
SexAll
SponsorIstanbul Saglik Bilimleri University Academic / other
Locations1 site (Istanbul, Uskudar)
Trial IDNCT06493123 on ClinicalTrials.gov

What this trial studies

This study investigates the effects of postoperative early mobilization and the use of Bottle-P.E.P. on respiratory function and physical capacity in patients who have undergone heart valve surgery. Participants will be randomly assigned to one of three groups: a control group receiving conventional rehabilitation, a group receiving conventional rehabilitation with Bottle-P.E.P., and a group receiving conventional rehabilitation with early mobilization. Evaluations will be conducted preoperatively and 5-7 days post-surgery, measuring respiratory parameters and functional capacity through pulmonary function tests and a 6-minute walk test. Statistical methods will be used to compare outcomes between the groups.

Who should consider this trial

Good fit: Ideal candidates are adults aged 25-75 who are undergoing heart valve surgery via sternotomy and have stable hemodynamic values.

Not a fit: Patients with significant comorbidities, such as uncontrolled arrhythmias or active malignancies, may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could enhance recovery and improve respiratory function in patients after heart valve surgery.

How similar studies have performed: Other studies have shown positive outcomes with early mobilization and rehabilitation techniques in postoperative cardiac patients, suggesting potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* After heart valve surgery: Patients undergoing valvular surgery via sternotomy
* Same surgical technique (from med-sternum)
* Age group (25-75 Y)
* Stable hemodynamic values (stable vital signs, normal temperature, etc.)
* Full awareness of time and space

Exclusion Criteria:

* Ejection Fraction 35 %
* Any Male/female patient \<25 or \>75
* Body Mass Index (BMI) ≥ 38 kg/m2
* Intubation time \>6 hours after surgery
* Uncontrolled arrhythmias
* Rheumatoid arthritis, other inflammatory and autoimmune diseases
* Active malignancy
* Cardiac pacemaker or defibrillator
* Mental health disorders
* Any postoperative complication (general muscle weakness, wound infection of the sternum or leg, stroke.)
* Refusal to assist in data collection

Where this trial is running

Istanbul, Uskudar

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Heart Valve Diseasesheart valve surgerybottle-P.E.P.early mobilizationcardiopulmonary rehabilitation
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.