Registry of stroke risk factors in Chinese patients with atrial fibrillation
Risk Factors for Stroke or Systemic Embolism in Chinese Patients with Non-Valvular Atrial Fibrillation Registry
This study is trying to find out which factors increase the risk of stroke in Chinese patients with atrial fibrillation to improve how we assess that risk.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 22000 (estimated) |
| Ages | 18 Years to 120 Years |
| Sex | All |
| Sponsor | China National Center for Cardiovascular Diseases Government |
| Locations | 1 site (Beijing, Beijing Municipality) |
| Trial ID | NCT05598632 on ClinicalTrials.gov |
What this trial studies
This observational study aims to validate existing stroke risk stratification models for patients with atrial fibrillation (AF) and to establish a new stroke risk assessment model using a nationwide AF-specific registry in China. It will enroll approximately 5,000 prospective and 22,000 retrospective patients, collecting extensive data on demographics, cardiovascular risk factors, treatment strategies, and outcomes over a follow-up period of about three years. The primary focus is on identifying factors associated with stroke or systemic embolic events in this population.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older with a documented history of atrial fibrillation.
Not a fit: Patients with moderate or severe mitral stenosis, mechanical heart valves, or those who have undergone AF ablation or left atrial appendage closure may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved risk assessment and management strategies for patients with atrial fibrillation, potentially reducing the incidence of stroke.
How similar studies have performed: Other studies have shown success in validating stroke risk models in atrial fibrillation populations, making this approach both relevant and promising.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18 years of age or older; male or female. * History of documented atrial fibrillation. * Able to provide written informed consent. Exclusion Criteria: * Subjects with moderate or severe mitral stenosis or a mechanical heart valve * Subjects with previous or planned AF ablation. * Subjects with previous or planned left atrial appendage closure. * Subjects unable to cooperate with follow-up after assessment.
Where this trial is running
Beijing, Beijing Municipality
- Fuwai Hospital, CAMS & PUMC — Beijing, Beijing Municipality, China (Recruiting)
Study contacts
- Study coordinator: Zhe Zheng, MD, PhD
- Email: zhengzhe@fuwai.com
- Phone: +86-010-88396051
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.