Registry of South Asians with Coronary Plaque Assessment

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This registry aims to recruit South Asian individuals and non-South Asian controls to assess coronary plaque characteristics and understand the increased risk of coronary artery disease in South Asians. Participants will complete surveys on demographics and medical history, undergo blood collection, and have a coronary CT angiogram (CCTA) performed. The collected data will be combined with clinical information from electronic health records to generate insights and preliminary data for future studies focused on cardiovascular health in this high-risk population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Males and Females: Age 18 years or above
* South Asian (SA) adults through self-identification (South Asians to have both biological parents with ancestry from India, Pakistan, Sri Lanka, Nepal and Bangladesh)
* We also propose to enroll an equivalent number of individuals of other descent as a comparator group (Non SA Adult Volunteers)
* Sampling Method: Probability Sample

Exclusion Criteria:

* Under the age of 18 years
* Unable to give informed consent
* Impaired renal function: estimated glomerular filtration rate ≤ 45ml/min
* Baseline heart rate≥70 bpm or ≥66 bpm after beta blocker
* Body mass index (BMI) of 35 or greater
* Prior anaphylactic/non-anaphylactic reaction or other contraindication to iodinated contrast
* Anyone who cannot do CCTA for any reason
* Pregnancy

Where it's running

• University of Texas Southwestern Medical Center
  Dallas, Texas, United States Recruiting

Study contacts

• Principal investigator: Anand Rohatgi, MD — University of Texas Southwestern Medical Center
• Study coordinator: Destiny Jones
• Email: SAHealth@UTSouthwestern.edu
• Phone: 214.645.2049

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.