Registry of Pediatric Patients Treated With Radiation Therapy
Proton and Photon Consortium Registry (PPCR): A Multi Center Registry of Pediatric Patients Treated With Radiation Therapy
This study is looking to gather information from kids who have had radiation therapy to see how different types of treatment affect their health and recovery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 5000 (estimated) |
| Ages | N/A to 21 Years |
| Sex | All |
| Sponsor | Massachusetts General Hospital Academic / other |
| Drugs / interventions | radiation, chemotherapy |
| Locations | 26 sites (Palo Alto, California and 25 other locations) |
| Trial ID | NCT01696721 on ClinicalTrials.gov |
What this trial studies
The Proton and Photon Consortium Registry (PPCR) aims to enroll pediatric patients who have received radiation therapy to better understand the demographics and treatment outcomes associated with different types of radiotherapy, specifically Proton Beam Radiation Therapy (PBRT) and Photon Therapy. This observational registry will collect comprehensive data on patient demographics, treatment history, and clinical outcomes to facilitate future research and comparisons of treatment efficacy. Patients will receive standard care as determined by their physicians, and their treatment responses and side effects will be documented over time. The collected data will help improve the understanding of radiation therapy's impact on pediatric cancer patients.
Who should consider this trial
Good fit: Ideal candidates are pediatric patients under the age of 22 who have been treated with radiation therapy at participating centers.
Not a fit: Patients who are over the age of 22 or have not received radiation therapy may not benefit from this registry.
Why it matters
Potential benefit: If successful, this registry could lead to improved treatment protocols and outcomes for pediatric patients undergoing radiation therapy.
How similar studies have performed: Other studies have shown promising results with similar approaches in collecting data on radiation therapy outcomes, indicating potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Eligibility Criteria: 1. Patients treated with radiation therapy at one of the participating centers 2. Age \< 22 at time of treatment start. 3. Patients may be enrolled regardless of previous local or systemic treatments received prior to enrollment in the PPCR. 4. Patients may be enrolled regardless of other current local or systemic treatments or disease extent. 5. Patients may be enrolled on the PPCR concurrently with another study or clinical trial.
Where this trial is running
Palo Alto, California and 25 other locations
- Stanford University — Palo Alto, California, United States (Recruiting)
- California Protons Cancer Therapy Center — San Diego, California, United States (Recruiting)
- University of California San Francisco — San Francisco, California, United States (Recruiting)
- University of Florida Health Proton Therapy Institute — Jacksonville, Florida, United States (Recruiting)
- Emory University — Atlanta, Georgia, United States (Recruiting)
- Northwestern Medicine Chicago Proton Center — Warrenville, Illinois, United States (Recruiting)
- Maryland Proton Treatment Center — Baltimore, Maryland, United States (Recruiting)
- Massachusetts General Hospital — Boston, Massachusetts, United States (Recruiting)
- Mayo Clinic — Rochester, Minnesota, United States (Recruiting)
- Washington University — St Louis, Missouri, United States (Recruiting)
- ProCure Proton Therapy Center- New Jersey — Somerset, New Jersey, United States (Recruiting)
- New York Proton Center — New York, New York, United States (Recruiting)
- State University of New York Upstate Medical Center — Syracuse, New York, United States (Recruiting)
- University of North Carolina — Chapel Hill, North Carolina, United States (Recruiting)
- The Ohio State University — Columbus, Ohio, United States (Recruiting)
- Cincinnati Children's Proton Therapy Center — Liberty Township, Ohio, United States (Recruiting)
- Oklahoma Proton Center — Oklahoma City, Oklahoma, United States (Recruiting)
- ProCure Proton Therapy Center- Oklahoma — Oklahoma City, Oklahoma, United States (Recruiting)
- University of Pennsylvania - Roberts Proton Therapy Center — Philadelphia, Pennsylvania, United States (Recruiting)
- Provision Center for Proton Therapy — Knoxville, Tennessee, United States (Active_not_recruiting)
- MD Anderson Cancer Center — Houston, Texas, United States (Recruiting)
- Texas Center for Proton Therapy — Irving, Texas, United States (Recruiting)
- University of Utah — Salt Lake City, Utah, United States (Recruiting)
- University of Washington- Seattle Cancer Care Alliance — Seattle, Washington, United States (Recruiting)
- Royal Adelaide Hospital — Adelaide, South Australia, Australia (Recruiting)
- University Health Network - Princess Margaret Hospital — Toronto, Ontario, Canada (Recruiting)
Study contacts
- Principal investigator: Torunn I Yock, MD — Massachusetts General Hospital
- Study coordinator: Torunn I Yock, MD
- Email: tyock@partners.org
- Phone: 6177266876
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.