Registry of patients with antiphospholipid antibodies
Official title: Constitution d'Une Collection d'Echantillons Biologiques Associee a Une Base de Donnees de Patients Possedant Des Anticorps Antiphospholipides
Run by Central Hospital, Nancy, France · NCT04308564 · Data updated 2026-11-12
This study is creating a registry to track adults with antiphospholipid antibodies to better understand their health and gather important information over time.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Central Hospital, Nancy, France Academic / other |
| Locations | 2 sites (Lille and 1 other locations) |
| Status | Recruiting |
| Started | April 12, 2021 |
| Main results expected | April 1, 2030 |
| Study ends | April 1, 2031 |
| Registry record updated | December 20, 2021 |
| Trial ID | NCT04308564 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18 to 60 who have persistent positivity for antiphospholipid antibodies.
✕Probably not a fit
Patients who are pregnant or unable to provide informed consent will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to create a comprehensive registry for patients who test positive for antiphospholipid antibodies. Utilizing a web-based application called REDCap, the study collects data on patient demographics, clinical characteristics, and laboratory results related to antiphospholipid syndrome. Eligible participants are adults aged 18 to 60 who have shown persistent positivity for specific antiphospholipid antibodies. Patients will be monitored annually for clinical updates and blood samples will be collected for further analysis.
Why it matters
Potential benefit: If successful, this registry could enhance understanding of antiphospholipid syndrome and improve patient management.
How similar studies have gone: While this approach is observational and builds on existing knowledge, similar registries have shown success in improving patient outcomes in related conditions.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * age between 18 and 60 years; * persistent (at least 12 weeks apart) aPL-positivity within 12 months prior to screening Exclusion Criteria: * no inform consent * impossible follow up * pregnancy
Where it's running
-
CHRU de Nancy
Nancy, France Recruiting -
CHRU de Lille
Lille, France Not yet recruiting
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Thrombocytopenia Trajectories in antiphospholipid syndrome
This study tests whether patterns in platelet counts over time can predict outcomes for adults with antiphospholipid syndrome.
-
BCT301 CAR-iT cell therapy for hard-to-treat autoimmune diseases
This early‑phase study tests whether off-the-shelf BCT301 CAR-iT cells can be given safely to adults with refractory autoimmune diseases to see if they can be tolerated and what dose works best.
-
Characterization of Autoreactive B Cells in Autoimmune Diseases and Immune Deficiencies
Researchers are testing to see how autoreactive B cells behave in people with autoimmune diseases or immune deficiencies to better understand how these cells may contribute to disease.
-
YTS109 cell therapy for relapsed or treatment‑resistant autoimmune diseases
This will try a single infusion of YTS109 immune cells in adults 18–65 with relapsed or treatment‑resistant autoimmune diseases such as lupus, Sjogren’s, systemic sclerosis, inflammatory myopathies, or ANCA‑associated vasculitis.
-
YTS109 cell therapy for relapsed or refractory autoimmune diseases
This will try a single infusion of YTS109 immune cells to see if they are safe and help adults 18–65 with relapsed or refractory lupus (including lupus nephritis), Sjogren's syndrome, inflammatory myopathy, or ANCA‑associated vasculitis.
-
Antiphospholipid syndrome in people 65 and older who had an ischemic stroke
This study will test whether routine blood testing for antiphospholipid antibodies in people aged 65 and over hospitalized with ischemic stroke or TIA can identify previously unrecognized antiphospholipid syndrome.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.