Registry of patients undergoing transcatheter aortic valve implantation in Kazakhstan

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This registry analyzes patients with aortic stenosis who have undergone transcatheter aortic valve implantation (TAVI) and surgical aortic valve replacement (SAVR) in Kazakhstan. The study aims to collect and compare outcomes, including survival rates, complications, and quality of life, over a follow-up period of up to four years. It will also assess the prevalence of aortic stenosis in different regions of Kazakhstan and evaluate the effectiveness of TAVI compared to SAVR. This is the first systematically collected database for TAVI in Central Asia.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients has given written informed Concent for study participation prior to procedure
* Patients with Aortic Valve stenosis
* Patients has severe degenerative or congenital aortic stenosis.
* Patients has symptomatic aortic stenosis as demonstrated by NYHA II or greater

Exclusion Criteria:

* Patients has active endocarditis
* Patients has history of cerebral vascular accident or transient ischemic attack within the past 3 months

Where it's running

• National Research Center for Cardiac Surgery
  Astana, Kazakhstan Recruiting

Study contacts

• Study coordinator: Abdurashid Mussayev, PhD
• Email: abdurashid.mussayev@gmail.com
• Phone: +77029997667

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Transcatheter Aortic Valve Replacement Registry for Outcomes and Quality Monitoring

  This registry collects information from hospitals about patients undergoing TAVR to see how care and outcomes compare to guidelines and nationwide data.

  Recruiting American College of Cardiology · Washington D.C., District of Columbia · NCT07908355

• Vericiguat to slow calcific aortic valve narrowing

  This trial tests whether vericiguat can slow the progression of mild-to-moderate calcific aortic valve stenosis compared with placebo.

  Recruiting Phase 2 West China Hospital · Chengdu, Sichuan · NCT07715279

• CHATEAU Registry: Real-world outcomes after TAVR

  This registry collects real-world data from adults who had TAVR between 2021 and 2025 to see how they do over time and how valve performance holds up.

  Recruiting Eunpyeong St. Mary's Hospital · Seoul · NCT07709858

• Impact of TAVR on kidney function in people with aortic valve disease

  This registry tests how trans-catheter aortic valve implantation affects kidney function and the risk of kidney injury in adults with aortic stenosis.

  Recruiting Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Roma, RM · NCT07626710

• Hydra THV Transfemoral Valve Implantation in Severe Aortic Stenosis

  This registry tests how safely and effectively the Hydra THV works when implanted through the femoral artery in adults with severe symptomatic aortic stenosis.

  Recruiting at 8 sites Fundación EPIC · Aravaca and 7 other locations · NCT07566624

• How the type of sedation affects recovery after TAVR

  This study will test whether three common sedation approaches (propofol, dexmedetomidine, or midazolam with fentanyl) change how people recover on the first day after transfemoral TAVR.

  Recruiting Phase 4 Endeavor Health · Glenview, Illinois · NCT07556523

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.