Registry of patients treated with transcatheter aortic valve implantation in Leipzig
Official title: An Observational Follow-up Assessment of Transcatheter Aortic Valve Implantation in Leipzig
Run by Helios Health Institute GmbH · NCT05015452 · Data updated 2026-11-12
This study collects information from patients who have received a new heart valve through a minimally invasive procedure in Leipzig to see how well the treatment works over time.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 20000 (estimated) |
| Sponsor | Helios Health Institute GmbH Academic / other |
| Locations | 1 site (Leipzig) |
| Status | Recruiting |
| Started | March 1, 2020 |
| Main results expected | December 31, 2030 |
| Study ends | December 31, 2030 |
| Registry record updated | October 9, 2024 |
| Trial ID | NCT05015452 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this registry are all patients who are treated with TAVI at the Heart Center in Leipzig.
✕Probably not a fit
Patients who do not undergo TAVI or are treated at other centers may not benefit from this registry.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This registry collects data on all patients who undergo transcatheter aortic valve implantation (TAVI) at the Heart Center in Leipzig, Germany. It includes routine clinical assessments and echocardiographic follow-ups to monitor patient outcomes and valve durability over a long-term period of up to 10 years. The aim is to gather comprehensive data that can help improve treatment protocols and patient care for those with aortic valve stenosis.
Why it matters
Potential benefit: If successful, this registry could enhance understanding of TAVI outcomes and improve treatment strategies for patients with aortic valve stenosis.
How similar studies have gone: Other registries and studies on TAVI have shown success in improving patient outcomes and understanding valve durability, indicating that this approach is supported by prior evidence.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * All patients treated with TAVI Exclusion Criteria: * None
Where it's running
-
Herzzentrum Leipzig
Leipzig, Germany Recruiting
Study contacts
- Study coordinator: Mohamed Abdel-Wahab, MD
- Email: mohamed.bdel-wahab@medizin.uni-leipzig.de
- Phone: +49 341 865 1428
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Transcatheter Aortic Valve Replacement Registry for Outcomes and Quality Monitoring
This registry collects information from hospitals about patients undergoing TAVR to see how care and outcomes compare to guidelines and nationwide data.
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Vericiguat to slow calcific aortic valve narrowing
This trial tests whether vericiguat can slow the progression of mild-to-moderate calcific aortic valve stenosis compared with placebo.
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CHATEAU Registry: Real-world outcomes after TAVR
This registry collects real-world data from adults who had TAVR between 2021 and 2025 to see how they do over time and how valve performance holds up.
-
Impact of TAVR on kidney function in people with aortic valve disease
This registry tests how trans-catheter aortic valve implantation affects kidney function and the risk of kidney injury in adults with aortic stenosis.
-
Hydra THV Transfemoral Valve Implantation in Severe Aortic Stenosis
This registry tests how safely and effectively the Hydra THV works when implanted through the femoral artery in adults with severe symptomatic aortic stenosis.
-
How the type of sedation affects recovery after TAVR
This study will test whether three common sedation approaches (propofol, dexmedetomidine, or midazolam with fentanyl) change how people recover on the first day after transfemoral TAVR.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.