Registry of patients in shock treated with vasopressin

Prospective Multicentre Observational Study of Patients Treated With Vasopressin in Critical Care Units

Observational Hospital Universitario 12 de Octubre · NCT06422975

This study looks at how vasopressin is used to treat patients in shock to see how it affects their recovery and overall health in the ICU.

Quick facts

Study typeObservational
Enrollment500 (estimated)
Ages18 Years and up
SexAll
SponsorHospital Universitario 12 de Octubre Academic / other
Locations24 sites (A Coruña and 23 other locations)
Trial IDNCT06422975 on ClinicalTrials.gov

What this trial studies

This observational study aims to characterize the clinical use of vasopressin in patients experiencing shock across multiple centers. It will collect data on the timing and duration of vasopressin and noradrenaline administration, as well as the clinical outcomes associated with their use. The study will also evaluate the reasons for initiating vasopressin therapy, its impact on noradrenaline dosing, cardiac function, and patient outcomes such as mortality and length of ICU stay.

Who should consider this trial

Good fit: Ideal candidates include adults over 18 years old who are in shock and require vasoconstrictor therapy.

Not a fit: Patients who do not consent to participate or are under 18 years old will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve the management of shock patients by optimizing vasopressin use and enhancing patient outcomes.

How similar studies have performed: While there have been studies on vasopressin use in shock, this specific observational approach to characterize its routine clinical application is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Any patient over 18 years of age who is in shock and requires the administration of vasoconstrictors, to whom vasopressin is administered in the operating theatre and/or critical care unit, according to best clinical practice.

Exclusion Criteria:

* Non-consent by patient/legal representatives

Where this trial is running

A Coruña and 23 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Vasopressin Causing Adverse Effects in Therapeutic UseShockVasopressor Adverse ReactionVasopressin DeficiencyVasopressin
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.