Registry of liver cancer patients in China
Official title: China Liver Cancer Clinical Registry Cohort Database (HEAL)
Run by Anhui Provincial Hospital · NCT06777485 · Data updated 2026-11-12
This study is creating a detailed database of liver cancer patients in China to help improve treatment and research for different types of liver cancer.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 10000 (estimated) |
| Sponsor | Anhui Provincial Hospital Government |
| Locations | 38 sites (Anqing, Anhui and 37 other locations) |
| Status | Recruiting |
| Started | January 1, 2025 |
| Main results expected | January 1, 2035 |
| Study ends | January 1, 2035 |
| Registry record updated | August 20, 2025 |
| Trial ID | NCT06777485 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults aged 18 and older diagnosed with liver cancer, either through imaging or pathology tests.
✕Probably not a fit
Patients with severe concurrent diseases or those on long-term immunosuppressive therapy may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to create a standardized clinical information database for patients diagnosed with various forms of liver cancer, including hepatocellular carcinoma and its variants. Led by the Department of Hepatobiliary Surgery at the First Affiliated Hospital of the University of Science and Technology of China, the study involves collaboration with multiple hospitals across the country. The database will facilitate high-quality real-world clinical studies and enhance clinical research in liver cancer management.
Why it matters
Potential benefit: If successful, this study could improve the understanding and treatment of liver cancer through enhanced data collection and analysis.
How similar studies have gone: While similar observational studies have been conducted, this specific registry approach is relatively novel in the context of liver cancer in China.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 18 years, no gender limit * Patients without surgery are initially diagnosed with hepatocellular carcinoma, intrahepatic cholangiocarcinoma, mixed hepatocellular carcinoma-cholangiocarcinoma, or metastatic hepatocellular carcinoma based on the results of imaging and laboratory tests, or patients with surgery are diagnosed with hepatocellular carcinoma, intrahepatic cholangiocarcinoma, mixed hepatocellular carcinoma-cholangiocarcinoma, or metastatic hepatocellular carcinoma based on the results of pathologic tests * Signed informed consent, good compliance, willingness to accept follow-up and provide blood and postoperative pathology residual samples Exclusion Criteria: * Combination of severe central nervous system disease, respiratory disease, autoimmune disease, chronic renal insufficiency, long-term use of immunosuppressive drugs, combination of severe uncontrolled infections * Concurrent active cardiovascular disease, cerebrovascular accident within 6 months, myocardial infarction, unstable angina pectoris, or congestive heart failure of class II or greater according to the New York Heart Association criteria, severe arrhythmia requiring medication * Pregnant or breastfeeding women * Participation in other therapeutic clinical trials during the course of the patient's illness in which the treatment cannot be specified or information about the treatment cannot be collected
Where it's running
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Anqing First People's Hospital
Anqing, Anhui, China Recruiting -
Anqing Municipal Hospital
Anqing, Anhui, China Recruiting -
Bengbu First People's Hospital
Bengbu, Anhui, China Recruiting -
The First Affiliated Hospital of Bengbu Medical University
Bengbu, Anhui, China Recruiting -
The Second Affiliated Hospital of Bengbu Medical College
Bengbu, Anhui, China Recruiting -
The People's Hospital of Bozhou
Bozhou, Anhui, China Recruiting
Show 32 more locations
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The People's Hospital of Chizhou
Chizhou, Anhui, China Recruiting -
The First People's Hospital of Chuzhou
Chuzhou, Anhui, China Recruiting -
No.2 People's Hospital of Fuyang City
Fuyang, Anhui, China Recruiting -
Fuyang Cancer Hospital
Fuyang, Anhui, China Recruiting -
Fuyang Fifth People's Hospital
Fuyang, Anhui, China Recruiting -
Fuyang People's Hospital
Fuyang, Anhui, China Recruiting -
Fuyang Sixth People's Hospital
Fuyang, Anhui, China Recruiting -
Funan County People's Hospital
Fuyang, Anhui, China Recruiting -
Taihe County People's Hospital
Fuyang, Anhui, China Recruiting -
Anhui province hospital
Hefei, Anhui, China Recruiting -
Anhui Provincial Cancer Hospital
Hefei, Anhui, China Recruiting -
Hefei Binhu Hospital
Hefei, Anhui, China Recruiting -
Hefei First People's Hospital
Hefei, Anhui, China Recruiting -
The First Affiliated Hospital of Anhui Medical University
Hefei, Anhui, China Recruiting -
The Second Hospital of Anhui Medical University
Hefei, Anhui, China Recruiting -
The Second People's Hospital of Hefei
Hefei, Anhui, China Recruiting -
Anhui Second People's Hospital
Hefei, Anhui, China Recruiting -
Huaibei Mining General Hospital
Huaibei, Anhui, China Recruiting -
Huaibei People's Hospital
Huaibei, Anhui, China Recruiting -
Huainan First People's Hospital
Huainan, Anhui, China Recruiting -
Huainan Oriental Hospital
Huainan, Anhui, China Recruiting -
Huainan Sunshine Xinkang Hospital
Huainan, Anhui, China Recruiting -
Huainan Xinhua Hospital
Huainan, Anhui, China Recruiting -
Huangshan City People's Hospital
Huangshan City, Anhui, China Recruiting -
Huangshan Shoukang Hospital
Huangshan City, Anhui, China Recruiting -
Lu'an People's Hospital
Lu'an, Anhui, China Recruiting -
Suzhou Hospital of Anhui Medical University
Suzhou, Anhui, China Recruiting -
Tongling People's Hospital
Tongling, Anhui, China Recruiting -
The Second People's Hospital of Wuhu
Wuhu, Anhui, China Recruiting -
The First Affiliated Hospital of Wannan Medical College
Wuhu, Anhui, China Recruiting -
Xuancheng People's Hospital
Xuancheng, Anhui, China Recruiting -
Henan Provincial People's Hospital
Zhengzhou, Henan, China Recruiting
Study contacts
- Study coordinator: Ji-Zhou Wang, MD PhD
- Email: wangjoe@ustc.edu.cn
- Phone: +86 13836135864
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DRAGON: International registry for patients who had combined portal and hepatic vein embolization before liver surgery
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.