Registry of Chinese Patients with Marginal Zone Lymphoma
Official title: The Effectiveness and Safety of Different Treatment Modalities in Real-World Clinical Practice Among Chinese Patients with Marginal Zone Lymphoma: a Prospective, Observational, Multi-center Study
Run by Ruijin Hospital · NCT06534463 · Data updated 2026-11-12
This study looks at how Chinese patients with marginal zone lymphoma are treated in real life to see how well those treatments work and how they affect patients' quality of life.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 14 Years and up |
| Sex | All |
| Enrollment | 500 (estimated) |
| Sponsor | Ruijin Hospital Academic / other |
| Locations | 1 site (Shanghai, Shanghai Municipality) |
| Status | Recruiting |
| Started | August 2, 2024 |
| Main results expected | March 1, 2029 |
| Study ends | September 1, 2029 |
| Registry record updated | December 3, 2024 |
| Trial ID | NCT06534463 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include individuals diagnosed with marginal zone lymphoma who meet the treatment indications.
✕Probably not a fit
Patients who do not have marginal zone lymphoma or those deemed unsuitable by the investigator will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study evaluates the real-world treatment approaches and their effectiveness and safety for Chinese patients diagnosed with marginal zone lymphoma. It aims to gather data on patient characteristics and assess health-related quality of life. Treatment regimens will be determined by physicians based on standard clinical practices and drug labels in China. The study will provide insights into how marginal zone lymphoma is managed in a real-world setting.
Why it matters
Potential benefit: If successful, this study could enhance understanding of effective treatment strategies for marginal zone lymphoma in Chinese patients.
How similar studies have gone: While this study focuses on a specific population, similar observational studies have successfully provided valuable insights into treatment effectiveness in various cancers.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Be diagnosed as MZL * Meet the treatment indications for MZL Exclusion Criteria: * Any reason that, in the investigator's opinion, makes the participant unsuitable to participate in this study.
Where it's running
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Shanghai Ruijin Hospital
Shanghai, Shanghai Municipality, China Recruiting
Study contacts
- Study coordinator: Weili Zhao
- Email: zwl_trial@163.com
- Phone: +862164370045
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Nemtabrutinib plus rituximab for marginal zone lymphoma
This phase 2 trial tests whether combining nemtabrutinib with rituximab can help people with marginal zone lymphoma.
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Orelabrutinib for adults with early-stage untreated marginal zone lymphoma
This trial will try orelabrutinib, a selective oral BTK inhibitor, as first-line treatment for adults with stage I–II marginal zone lymphoma to see if it works and is safe.
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Zanubrutinib plus rituximab as first-line treatment for marginal zone lymphoma
This tests whether combining zanubrutinib and rituximab is effective and safe as first-line treatment for people with CD20-positive marginal zone lymphoma who have not received prior systemic therapy.
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Rituximab and Tafasitamab with Allogeneic NK Cells for relapsed or refractory B-cell NHL
This trial tests whether giving allogeneic NK cells with Rituximab, Tafasitamab, and IL-2 can help people with relapsed or refractory B-cell non-Hodgkin lymphoma who have tried at least two prior therapies.
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Reduced-dose radiation therapy for people with follicular or marginal zone lymphoma
This trial will test whether very low-dose radiation controls stage I–II follicular or marginal zone lymphoma as well as standard-dose radiation while causing fewer side effects.
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Personalized exercise and nutrition program to reduce cancer-related fatigue
This program will try a personalized exercise and diet plan to reduce fatigue for adults with indolent lymphomas (including CLL/SLL and follicular lymphoma).
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.