Registry for tracking outcomes of transcatheter aortic valve replacement
Official title: Society of Thoracic Surgeons and American College of Cardiology Transcatheter Valve Therapy Registry (STS/ACC TVT Registry).
Run by The Society of Thoracic Surgeons · NCT01737528 · Data updated 2026-11-12
This study is tracking how well transcatheter aortic valve replacement works for people with severe heart valve problems to help improve patient care and outcomes.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 16000 (estimated) |
| Sponsor | The Society of Thoracic Surgeons Academic / other |
| Locations | 1 site (Washington D.C., District of Columbia) |
| Status | Recruiting |
| Started | June 2012 |
| Main results expected | June 2035 |
| Study ends | June 2035 |
| Registry record updated | August 25, 2022 |
| Trial ID | NCT01737528 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this registry are adults aged 18 years or older with severe symptomatic native aortic valve stenosis who are inoperable or at high risk for open aortic valve replacement.
✕Probably not a fit
Patients who do not have severe symptomatic aortic valve stenosis or are not considered high risk for surgery may not benefit from this registry.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The TVT Registry is a national surveillance system designed to monitor patient safety and real-world outcomes associated with transcatheter aortic valve replacement (TAVR) for patients with severe symptomatic aortic valve stenosis. Participating hospitals submit patient-level data to assess the quality of care and outcomes for those undergoing this innovative procedure. The registry aims to provide periodic reports to healthcare providers to improve care quality and support further research based on collected data.
Why it matters
Potential benefit: If successful, this registry could enhance the safety and effectiveness of transcatheter aortic valve replacement, ultimately improving patient outcomes.
How similar studies have gone: Other studies utilizing registry-based approaches for monitoring outcomes in cardiac procedures have shown success, indicating that this methodology is both effective and valuable.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion criteria: * 18 years or older
Where it's running
-
American College of Cardiology
Washington D.C., District of Columbia, United States Recruiting
Study contacts
- Principal investigator: John D Carroll, MD — American College of Cardiology
- Study coordinator: Joan Michaels
- Email: jmichael@acc.org
- Phone: (202) 375 6309
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Transcatheter Aortic Valve Replacement Registry for Outcomes and Quality Monitoring
This registry collects information from hospitals about patients undergoing TAVR to see how care and outcomes compare to guidelines and nationwide data.
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Vericiguat to slow calcific aortic valve narrowing
This trial tests whether vericiguat can slow the progression of mild-to-moderate calcific aortic valve stenosis compared with placebo.
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CHATEAU Registry: Real-world outcomes after TAVR
This registry collects real-world data from adults who had TAVR between 2021 and 2025 to see how they do over time and how valve performance holds up.
-
Impact of TAVR on kidney function in people with aortic valve disease
This registry tests how trans-catheter aortic valve implantation affects kidney function and the risk of kidney injury in adults with aortic stenosis.
-
Hydra THV Transfemoral Valve Implantation in Severe Aortic Stenosis
This registry tests how safely and effectively the Hydra THV works when implanted through the femoral artery in adults with severe symptomatic aortic stenosis.
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How the type of sedation affects recovery after TAVR
This study will test whether three common sedation approaches (propofol, dexmedetomidine, or midazolam with fentanyl) change how people recover on the first day after transfemoral TAVR.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.