Registry for tracking leptospirosis cases
Leptospirosis Registry - LeptoScope
This study is gathering information from patients with invasive leptospirosis to better understand the disease and improve future treatments.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 200 (estimated) |
| Sex | All |
| Sponsor | University of Cologne Academic / other |
| Locations | 1 site (Cologne, North Rhine-Westphalia) |
| Trial ID | NCT04288674 on ClinicalTrials.gov |
What this trial studies
The Leptospirosis Registry - LeptoScope aims to gather comprehensive data on the epidemiology, clinical course, and prognostic factors of invasive leptospirosis disease. This observational study will collect retrospective data on demographics, underlying diseases, and duration of hospitalization from patients diagnosed with invasive leptospirosis. By analyzing this data, the study seeks to enhance understanding of the disease's impact and inform future treatment strategies. The registry will also include matched case controls to provide comparative insights.
Who should consider this trial
Good fit: Ideal candidates for this study include individuals with clinical evidence of invasive leptospirosis, either confirmed through laboratory testing or showing significant clinical signs.
Not a fit: Patients with non-invasive leptospirosis infections or those without clinical evidence of dissemination may not benefit from this study.
Why it matters
Potential benefit: If successful, this registry could lead to improved understanding and management of leptospirosis, potentially reducing morbidity and mortality associated with the disease.
How similar studies have performed: While there have been studies on leptospirosis, this registry approach is relatively novel and aims to fill significant gaps in current knowledge.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Cultural, serological, molecular or histological evidence of invasive leptospirosis diseases * Clinical signs of disseminated leptospirosis disease without cultural, serological, molecular or histological evidence * Case controls: Matching procedures for controls: Particularly, case controls will be included at the same hospitals that conduced cases based on matching of demographics, underlying diseases and duration of hospitalization (i.e. one control per case, both in the same hospital). Exclusion Criteria: * Colonization or other non-invasive infection * Cultural, serological, molecular or histological evidence without dissemination
Where this trial is running
Cologne, North Rhine-Westphalia
- University Hospital of Cologne — Cologne, North Rhine-Westphalia, Germany (Recruiting)
Study contacts
- Principal investigator: Felix Köhler, MD — University Hospital of Cologne
- Study coordinator: Felix Köhler, MD
- Email: felix.koehler@uk-koeln.de
- Phone: +4922147897222
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.