Community spread of multiple infectious diseases in Cambodia from a One Health perspective
Official title: Risk Assessment of Community Spread of Multiple Endemic Infectious Diseases in a One Health Perspective
Run by Institut Pasteur du Cambodge · NCT07358910 · Data updated 2026-11-12
This project will test how common and connected dengue, chikungunya, Zika, Japanese encephalitis, and West Nile infections are among people, animals, and the environment across Cambodia.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 2 Years to 75 Years |
| Sex | All |
| Enrollment | 10000 (estimated) |
| Sponsor | Institut Pasteur du Cambodge Academic / other |
| Locations | 1 site (Phnom Penh, Phnom Penh) |
| Status | Recruiting |
| Started | December 18, 2025 |
| Main results expected | April 16, 2026 |
| Study ends | September 30, 2027 |
| Registry record updated | January 22, 2026 |
| Trial ID | NCT07358910 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal participants are residents of selected Cambodian villages who have lived there more than six months, are between 2 and 75 years old, and can provide appropriate consent or parental consent and assent for minors.
✕Probably not a fit
People who live outside the selected Cambodian communities, are younger than 2 or older than 75, are under guardianship or deprived of liberty, unable to consent, or seeking direct medical treatment rather than survey participation are unlikely to benefit from this observational project.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
RACSMEI is a nationwide One Health, multi-pathogen effort using a nationally representative population survey combined with animal and environmental sampling. The project pairs social-science interviews with multiplex laboratory diagnostics to test for 57 priority pathogens and builds a structured biobank and curated datasets. Mathematical modeling and integrated analysis will link burden, ecology, transmission patterns, and population immunity to inform public-health decisions. The program also includes capacity building and stakeholder engagement to strengthen national institutions and promote uptake of results.
Why it matters
Potential benefit: If successful, the project could enable targeted, culturally appropriate prevention and control measures and strengthen national surveillance to reduce infectious-disease burden.
How similar studies have gone: Similar multi-pathogen serosurveys and One Health approaches have produced useful public-health insights elsewhere, but a nationwide integrated effort covering 57 pathogens in Cambodia is novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Residency in the village for more than 6 months; * Age between 2 and 75 years old at the time of inclusion; * For adults: provision of written consent; * For children aged 2-17 years: written parental consent form, verbal assent from children aged 13-17 years; Exclusion Criteria: * Unable to understand or consent; * Under guardianship or deprived of liberty; * Medical conditions that impede survey participation; * Refusal to participate in the study.
Where it's running
-
Institut Pasteur du Cambodge
Phnom Penh, Phnom Penh, Cambodia Recruiting
Study contacts
- Principal investigator: Claude Flamand, Ph.D. — Institut Pasteur du Cambodge
- Study coordinator: Claude Flamand, Ph.D.
- Email: cflamand@pasteur-kh.org
- Phone: +855012333650
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.