Clinical trial Recruiting at 1 site Observational Ages 2 to 75

Community spread of multiple infectious diseases in Cambodia from a One Health perspective

Official title: Risk Assessment of Community Spread of Multiple Endemic Infectious Diseases in a One Health Perspective

Run by Institut Pasteur du Cambodge · NCT07358910 · Data updated 2026-11-12

This project will test how common and connected dengue, chikungunya, Zika, Japanese encephalitis, and West Nile infections are among people, animals, and the environment across Cambodia.

More Malaria trials

Quick facts

Study typeObservational
Ages2 Years to 75 Years
SexAll
Enrollment10000 (estimated)
SponsorInstitut Pasteur du Cambodge
Academic / other
Locations1 site (Phnom Penh, Phnom Penh)
StatusRecruiting
StartedDecember 18, 2025
Main results expectedApril 16, 2026
Study endsSeptember 30, 2027
Registry record updatedJanuary 22, 2026
Trial IDNCT07358910 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal participants are residents of selected Cambodian villages who have lived there more than six months, are between 2 and 75 years old, and can provide appropriate consent or parental consent and assent for minors.

Probably not a fit

People who live outside the selected Cambodian communities, are younger than 2 or older than 75, are under guardianship or deprived of liberty, unable to consent, or seeking direct medical treatment rather than survey participation are unlikely to benefit from this observational project.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

RACSMEI is a nationwide One Health, multi-pathogen effort using a nationally representative population survey combined with animal and environmental sampling. The project pairs social-science interviews with multiplex laboratory diagnostics to test for 57 priority pathogens and builds a structured biobank and curated datasets. Mathematical modeling and integrated analysis will link burden, ecology, transmission patterns, and population immunity to inform public-health decisions. The program also includes capacity building and stakeholder engagement to strengthen national institutions and promote uptake of results.

Why it matters

Potential benefit: If successful, the project could enable targeted, culturally appropriate prevention and control measures and strengthen national surveillance to reduce infectious-disease burden.

How similar studies have gone: Similar multi-pathogen serosurveys and One Health approaches have produced useful public-health insights elsewhere, but a nationwide integrated effort covering 57 pathogens in Cambodia is novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Residency in the village for more than 6 months;
* Age between 2 and 75 years old at the time of inclusion;
* For adults: provision of written consent;
* For children aged 2-17 years: written parental consent form, verbal assent from children aged 13-17 years;

Exclusion Criteria:

* Unable to understand or consent;
* Under guardianship or deprived of liberty;
* Medical conditions that impede survey participation;
* Refusal to participate in the study.

Where it's running

  • Institut Pasteur du Cambodge
    Phnom Penh, Phnom Penh, Cambodia
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.