Registry for rare head and neck cancers in Europe

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational registry aims to collect and analyze data on rare head and neck cancers, including nasopharynx, nasal cavity, salivary glands, and middle ear cancers. By gathering information from various healthcare providers and existing databases, the registry seeks to describe the natural history of these cancers, evaluate prognostic factors, assess treatment effectiveness, and measure quality of care indicators. The initiative is part of the European Reference Network on rare adult solid cancers, which aims to improve research and care for these uncommon conditions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with epithelial tumours of nasopharynx; nasal cavity and paranasal sinuses; salivary gland cancer in large and small salivary glands; and middle ear (i.e. squamous carcinoma; adenocarcinoma; neuroendocrine; adenosquamous carcinoma, teratocarcinosarcoma, NUT carcinoma, odontogenic tumors) + neuroendocrine and adenocarcinoma in hypopharynx; oropharynx; larynx; oral cavity and lip + odontogenic carcinoma in oral cavity.
* Adult patients (aged ≥18 years).
* Diagnosis performed or verified by the expert centre entering the patient information in the registry.
* Patients entering the HCP at any clinical phase of the disease (diagnosis, treatment of primary cancer, treatment of recurrence, treatment of M+ etc.). The HCP can decide, based on its resources, the number of patients on whom it can collect data.
* New patients managed by the HCP from 2021 onwards plus patients managed by the HCP, who are actively followed up at the hospital, with year of diagnosis dating back to maximum 2018.

Exclusion Criteria:

• Patients (aged \< 18 years)

Where it's running

• IRCCS Ospedale Policlinico San Martino
  Genova, Genova, Italy Recruiting
• IRCCS Ospedale San Raffaele
  Milan, Milano, Italy Recruiting
• IRCCS Istituto Europeo di Oncologia
  Milan, Milano, Italy Recruiting
• IRCCS Istituto Clinica Humanitas
  Rozzano, Milano, Italy Recruiting
• Fondazione IRCCS Istituto Nazionale dei Tumori
  Milan, Milan, Italy Recruiting
• Centro Nazionale di Adroterapia Oncologica
  Pavia, Pavia, Italy Recruiting

Study contacts

• Principal investigator: Annalisa Trama, MD — Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
• Study coordinator: Lucia Buratti
• Email: EURACANregistry@istitutotumori.mi.it
• Phone: 0223902901

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.