Registry for Preterm Premature Rupture of Membranes
Official title: Patient Registry for Women Diagnosed With Preterm Premature Rupture of Membranes or PPROM During Pregnancy
Run by American Alliance for pProm Support · NCT02997345 · Data updated 2026-11-12
This study is collecting information about pregnancies affected by early water breaking to see what causes it and how to improve care for both moms and babies.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 14 Years to 55 Years |
| Sex | Women only |
| Enrollment | 3000 (estimated) |
| Sponsor | American Alliance for pProm Support Academic / other |
| Locations | 1 site (Denver, Colorado) |
| Status | Recruiting |
| Started | July 2013 |
| Main results expected | December 2030 |
| Study ends | December 2030 |
| Registry record updated | March 16, 2026 |
| Trial ID | NCT02997345 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this registry are women diagnosed with Preterm Premature Rupture of Membranes before 37 weeks of pregnancy.
✕Probably not a fit
Patients who do not have a clinical diagnosis of PPROM or those diagnosed with PROM beyond 37 weeks may not benefit from this registry.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The PPROM Registry aims to gather comprehensive data on pregnancies affected by Preterm Premature Rupture of Membranes (PPROM) before 37 weeks. It seeks to identify potential causes of PPROM, evaluate management trends, and assess both maternal and fetal care practices. By analyzing short-term and long-term outcomes of affected pregnancies, the registry aims to fill gaps in current knowledge and improve care protocols. This observational study will provide a large cohort of data, which is currently lacking in existing literature.
Why it matters
Potential benefit: If successful, this registry could lead to improved management strategies and outcomes for pregnancies affected by PPROM.
How similar studies have gone: This registry represents a novel approach, as few recent studies have focused on PPROM with large sample sizes and comprehensive follow-up.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Women diagnosed with Preterm Premature Rupture of Membranes (PPROM) prior to 37 weeks of pregnancy Exclusion Criteria: * Those without a clinical diagnosis or confirmation of PPROM in pregnancy * Diagnosis of PROM beyond 37 weeks of pregnancy
Where it's running
-
Www.Aapprom.Org/the-Registry
Denver, Colorado, United States Recruiting
Study contacts
- Study coordinator: Erin Thatcher
- Phone: (740) 837-7766
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.