Clinical trial Recruiting at 1 site Observational Ages 14 to 55 Women only

Registry for Preterm Premature Rupture of Membranes

Official title: Patient Registry for Women Diagnosed With Preterm Premature Rupture of Membranes or PPROM During Pregnancy

Run by American Alliance for pProm Support · NCT02997345 · Data updated 2026-11-12

This study is collecting information about pregnancies affected by early water breaking to see what causes it and how to improve care for both moms and babies.

More Premature Birth trials

Quick facts

Study typeObservational
Ages14 Years to 55 Years
SexWomen only
Enrollment3000 (estimated)
SponsorAmerican Alliance for pProm Support
Academic / other
Locations1 site (Denver, Colorado)
StatusRecruiting
StartedJuly 2013
Main results expectedDecember 2030
Study endsDecember 2030
Registry record updatedMarch 16, 2026
Trial IDNCT02997345 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this registry are women diagnosed with Preterm Premature Rupture of Membranes before 37 weeks of pregnancy.

Probably not a fit

Patients who do not have a clinical diagnosis of PPROM or those diagnosed with PROM beyond 37 weeks may not benefit from this registry.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The PPROM Registry aims to gather comprehensive data on pregnancies affected by Preterm Premature Rupture of Membranes (PPROM) before 37 weeks. It seeks to identify potential causes of PPROM, evaluate management trends, and assess both maternal and fetal care practices. By analyzing short-term and long-term outcomes of affected pregnancies, the registry aims to fill gaps in current knowledge and improve care protocols. This observational study will provide a large cohort of data, which is currently lacking in existing literature.

Why it matters

Potential benefit: If successful, this registry could lead to improved management strategies and outcomes for pregnancies affected by PPROM.

How similar studies have gone: This registry represents a novel approach, as few recent studies have focused on PPROM with large sample sizes and comprehensive follow-up.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Women diagnosed with Preterm Premature Rupture of Membranes (PPROM) prior to 37 weeks of pregnancy

Exclusion Criteria:

* Those without a clinical diagnosis or confirmation of PPROM in pregnancy
* Diagnosis of PROM beyond 37 weeks of pregnancy

Where it's running

  • Www.Aapprom.Org/the-Registry
    Denver, Colorado, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.