Clinical trial Recruiting at 20 sites Observational Ages 18 and up

Registry for patients with Status Epilepticus in critical care

Official title: Status Epilepticus in the Critically Ill Patients

Run by Ictal Group · NCT03457831 · Data updated 2026-11-12

This study is trying to gather information about patients with Status Epilepticus in critical care to see how they are treated and what outcomes they have.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment1000 (estimated)
SponsorIctal Group
Academic / other
Locations20 sites (Angoulême and 19 other locations)
StatusRecruiting
StartedFebruary 28, 2018
Main results expectedDecember 31, 2028
Study endsDecember 31, 2028
Registry record updatedOctober 22, 2020
Trial IDNCT03457831 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults aged 18 years and older who are experiencing Status Epilepticus.

Probably not a fit

Patients under 18 years of age or those with postanoxic status epilepticus will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to create a prospective registry for patients experiencing Convulsive and Non-Convulsive Status Epilepticus (SE) in critical care settings. It involves collecting comprehensive data on patient demographics, seizure characteristics, treatment timelines, and outcomes, including vital status and Glasgow Outcome Scale scores at various time points. The study will utilize standardized forms to ensure consistency in data collection across multiple hospitals. The goal is to better understand the circumstances and treatment of SE in critically ill patients.

Why it matters

Potential benefit: If successful, this study could improve the management and outcomes of critically ill patients suffering from Status Epilepticus.

How similar studies have gone: While there have been studies on Status Epilepticus, this registry approach is relatively novel and aims to fill gaps in existing knowledge.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* SE defined as 5 min or more of (i) continuous clinical and/or electrographic seizure activity or (ii) recurrent seizure activity without recovery (returning to baseline) between seizures.
* age \>= 18 years

Exclusion Criteria:

* age \< 18 years
* postanoxic status epilepticus

Where it's running

  • CH Angouleme - Service de réanimation polyvalente
    Angoulême, France
    Recruiting
  • CH de Beauvais - Service de réanimation polyvalente
    Beauvais, France
    Recruiting
  • CH de Bethune - Service de Réanimation et Surveillance continue
    Beuvry, France
    Recruiting
  • Centre Hospitalier Universitaire Régional
    Brest, France
    Recruiting
  • CH Brive La Gaillarde - Service de réanimation - USC
    Brive-la-Gaillarde, France
    Recruiting
  • CH de Cannes
    Cannes, France
    Recruiting
Show 14 more locations
  • CH Public du Cotentin - Service de Réanimation - Médecin intensive
    Cherbourg, France
    Recruiting
  • CHU Beaujon
    Clichy, France
    Recruiting
  • Hopitaux Universitaires Henri Mondor - Service d'anesthésie et des réanimations chirurgicales, Unité d'anesthésie-réanimation chirurgical cardiovasculaire
    Créteil, France
    Recruiting
  • Centre Hospitalier de Dieppe
    Dieppe, France
    Recruiting
  • Centre Hospitalier Universitaire de Dijon
    Dijon, France
    Recruiting
  • CH de La Rochelle - Service de réanimation - USC
    La Rochelle, France
    Recruiting
  • Intensive Care Unit - Versailles Hospital
    Le Chesnay, France
    Recruiting
  • Hôpital privé Jacques Cartier - Service de réanimation médico chirurgicale
    Massy, France
    Recruiting
  • Groupe Hospitalier Sud Ile de France - Service de Réanimation - Médecin intensive
    Melun, France
    Recruiting
  • Centre Hospitalier Universitaire de Nantes
    Nantes, France
    Recruiting
  • Groupe Hospitalier Paris Saint Joseph - Service de réanimation médico chirurgicale
    Paris, France
    Recruiting
  • HP Claude Galien - Service de Réanimation Polyvalente
    Quincy-sous-Sénart, France
    Recruiting
  • Centre hospitalier de Roanne - Service de Réanimation - Soins continus
    Roanne, France
    Recruiting
  • Centre Hospitalier de Toulon
    Toulon, France
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

  • Recovery after coma from serious brain injury or illness

    This observational study will follow adults who are unconscious due to a serious brain illness or injury to see what medical, neurological, psychological, and social factors are linked with recovery over time.

    Recruiting University of California, San Francisco · San Francisco, California · NCT07614074

  • Augmented kidney clearance in neurocritical care

    This project will test whether adults in the neuro-ICU with severe brain injury, stroke, seizures, or brain infections have faster kidney clearance (ARC) that can lower antiseizure and antibiotic drug levels.

    Recruiting at 3 sites University of Alberta · Lexington, Kentucky and 2 other locations · NCT07410624

  • Ketamine added to levetiracetam to stop prolonged convulsive seizures

    This trial will test whether giving ketamine (two different doses) along with levetiracetam helps stop benzodiazepine-refractory status epilepticus in people age 1 and older.

    Recruiting at 36 sites Phase 3 University of Virginia · Birmingham, Alabama and 62 other locations · NCT06907173

  • Improving prognosis for patients with Status Epilepticus

    This study is trying to find blood markers that can help predict how well patients with Status Epilepticus will recover in the ICU and how their thinking skills may change after they leave the hospital.

    Recruiting London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · London, Ontario · NCT06590883

  • Using Rapid-Response EEG to Diagnose Seizures in Children

    This study is testing if a new quick EEG device can help doctors diagnose seizures in children faster than the standard method.

    Recruiting Children's Hospital at Montefiore · The Bronx, New York · NCT06564662

  • Two-way video support for paramedics caring for infants with life-threatening breathing problems.

    This project will test whether a two-way video link with pediatric emergency doctors helps paramedics give better care to infants with life-threatening breathing problems during transport.

    Recruiting at 4 sites Boston Medical Center · Los Angeles, California and 8 other locations · NCT06441760

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.