Registry for patients with recurrent vasovagal syncope and bradyarrhythmias

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The CNA-FWRD Registry is an international prospective observational multicenter registry that focuses on patients experiencing symptomatic vasovagal syncope and bradyarrhythmias. Participants are managed through routine care, which may include medical therapy, radiofrequency catheter ablation of ganglionated plexi, or permanent pacemaker implantation. Eligible patients are under 60 years old and have symptoms that are refractory to standard treatments. The study will track outcomes for those undergoing procedures as well as those in a control group awaiting intervention.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* symptomatic vasovagal syncope or symptomatic bradyarrhythmia refractory to behavioral and medical measures
* age \< 60 years

Exclusion Criteria:

* age \> 60 years
* intra-/infra-Hisian AV block
* intrinsic sinus node disease
* history of supraventricular tachycardia
* history of ventricular tachycardia
* presence of structural heart disease related
* prior history of catheter ablation
* presence of inheritable arrhythmic conditions
* orthostatic hypotension on HUTT test
* abnormal thyroid function levels
* Proven indication for permanent pacemaker implantation

Where it's running

• Rush University Medical Centert
  Chicago, Illinois, United States Recruiting

Study contacts

• Study coordinator: Alexander Mazur, MD
• Email: alexander_mazur@rush.edu
• Phone: 312-942-5020

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.