Registry for patients with lymphatic anomalies

Lymphatic Anomalies Registry for the Assessment of Outcome Data

Observational Boston Children's Hospital · NCT02399527

This study is collecting information from people with lymphatic anomalies to see how these conditions affect their health and treatment over time.

Quick facts

Study typeObservational
Enrollment1000 (estimated)
SexAll
SponsorBoston Children's Hospital Academic / other
Locations1 site (Boston, Massachusetts)
Trial IDNCT02399527 on ClinicalTrials.gov

What this trial studies

This registry aims to collect and analyze data on patients diagnosed with various lymphatic anomalies, including conditions like Gorham-Stout Disease and CLOVES Syndrome. Participants will undergo a brief interview and provide access to their medical records to help researchers understand the natural history, outcomes, and treatment responses associated with these rare conditions. The registry will facilitate annual follow-ups to gather ongoing data on patient health, treatments, and quality of life. By creating a comprehensive database, the project seeks to improve care and predict responses to therapies for patients with lymphatic anomalies.

Who should consider this trial

Good fit: Ideal candidates include individuals diagnosed with complex vascular tumors, malformations, or overgrowth syndromes that have a significant lymphatic component.

Not a fit: Patients without a clinical diagnosis of a lymphatic anomaly or those with unrelated conditions may not benefit from this registry.

Why it matters

Potential benefit: If successful, this registry could enhance understanding and management of lymphatic anomalies, leading to improved patient outcomes.

How similar studies have performed: While this registry approach is relatively novel for lymphatic anomalies, similar registries for other rare conditions have shown success in improving patient care and outcomes.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Clinical diagnosis of complex vascular tumor, malformation or overgrowth syndrome with significant lymphatic component

Where this trial is running

Boston, Massachusetts

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Lymphatic MalformationGeneralized Lymphatic AnomalyCentral Conducting Lymphatic AnomalyCLOVES SyndromeGorham-Stout DiseaseBlue Rubber Bleb Nevus SyndromeKaposiform LymphangiomatosisKaposiform Hemangioendothelioma/Tufted Angioma
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.