Registry for patients with congenital heart disease

Invasive Hemodynamic Control Cohort for The Mayo Clinic Adult Congenital Heart Disease (MACHD) Registry

Observational Mayo Clinic · NCT05849025

This study is gathering information from adults with congenital heart disease to better understand their health and improve care for them.

Quick facts

Study typeObservational
Enrollment50 (estimated)
Ages18 Years and up
SexAll
SponsorMayo Clinic Academic / other
Locations1 site (Rochester, Minnesota)
Trial IDNCT05849025 on ClinicalTrials.gov

What this trial studies

This observational study aims to gather comparative data for the Mayo Clinic Adult Congenital Heart Disease Registry. It will involve patients who meet specific health criteria, including those with a BMI of 30 or less and stable blood pressure levels. Participants will undergo assessments to ensure they can consent and meet kidney function requirements. The study will help enhance understanding of congenital heart disease in adults.

Who should consider this trial

Good fit: Ideal candidates are adults with congenital heart disease who meet specific health criteria and can undergo an MRI.

Not a fit: Patients with a history of cardiovascular disease or those currently taking cardiac medication may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve the management and treatment strategies for adults with congenital heart disease.

How similar studies have performed: Other studies have shown success in utilizing registries for congenital heart disease, indicating this approach is supported by prior research.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Capacity to Consent
* BMI \</= 30
* Systolic BP \</= 140mmHg
* Diastolic BP \</= 90
* eGFR \> 30 (within prior 3 months) to confirm kidney function
* Able to undergo an MRI

Exclusion Criteria:

* History of Cardiovascular disease that may affect the results of the testing performed.
* Any Current orthopedic limitations
* Currently taking any cardiac medication
* Pregnancy

Where this trial is running

Rochester, Minnesota

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions HealthyCongenital Heart Disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.