Registry for patients with acute coronary syndrome
Cardiac Biochemical and Omics-based Biomarkers in Patients Presenting Symptoms of Acute Coronary Syndrome in the Emergency Department (ACS Registry)
This study is collecting information about patients with acute coronary syndrome at the University Hospital of Heidelberg to better understand their characteristics and treatment.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 2500 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University Hospital Heidelberg Academic / other |
| Locations | 1 site (Heidelberg, Baden-Wurttemberg) |
| Trial ID | NCT06128317 on ClinicalTrials.gov |
What this trial studies
This registry aims to assess the real-world prevalence, demographic characteristics, and management of patients presenting with acute coronary syndrome at the University Hospital of Heidelberg. It involves comprehensive data collection, including clinical parameters and blood samples for analysis of both established and novel biomarkers. The registry is managed by the Department of Internal Medicine III and will serve as a foundation for future clinical studies. Follow-up will be conducted through medical report reviews, phone calls, and postal queries to track patient outcomes.
Who should consider this trial
Good fit: Ideal candidates include adults aged 18 and older presenting with symptoms of acute coronary syndrome or elevated troponin levels.
Not a fit: Patients with acute conditions requiring immediate treatment or those unable to provide informed consent due to mental illness or pregnancy may not benefit from this registry.
Why it matters
Potential benefit: If successful, this registry could enhance understanding of acute coronary syndrome and improve patient management strategies.
How similar studies have performed: Other observational studies have successfully characterized acute coronary syndrome, suggesting this approach is validated in the field.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: The study will include consecutive patients who present to the cardiology emergency department at Heidelberg University Hospital with symptoms of acute coronary syndrome or a troponin increase (hs-TnT \>14 ng/L). Additional inclusion criteria are a minimum age of 18 years and providing informed consent through written consent to participate in the study. The following medical conditions are intended to be distinguished from one another: * Acute myocardial infarction * Unstable angina pectoris * Myocarditis * Heart failure * Cardiomyopathies * Pulmonary embolism * Renal insufficiency * Supraventricular and ventricular tachycardias * Hypertensive crisis * Non-cardiac chest pain Exclusion Criteria: Exclusion criteria are defined according to GCP (Good Clinical Practice), i.e., mental illnesses/dementia (lack of capacity to provide informed consent), pregnancy/breastfeeding, as well as acute conditions requiring immediate treatment (e.g., cardiogenic shock).
Where this trial is running
Heidelberg, Baden-Wurttemberg
- University Hospital of Heidelberg — Heidelberg, Baden-Wurttemberg, Germany (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.