Registry for patients undergoing transcatheter mitral valve replacement

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The Hamburg TranscathEteR Mitral Valve REplacement RegiStry (HERMES) is a prospective cohort registry designed to collect follow-up data on the short- and long-term outcomes of patients with significant mitral valve disease who are screened for transcatheter mitral valve replacement (TMVR). This study focuses on the durability and function of implanted bioprostheses and compares various treatment strategies for patients based on their screening results. It aims to provide valuable insights into the effectiveness of TMVR, particularly for patients at high surgical risk with suboptimal anatomy for other interventions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Ability to provide written informed consent in accordance with Good Epidemiological Practice and local legislation.
* Individuals over the age of 18 years.
* Patients with clinically relevant mitral valve disease, who undergo screening for TMVR.

Exclusion Criteria:

* Insufficient knowledge of the German language, to understand study documents and interview without translation
* Physical or psychological incapability to cooperate in the investigation

Where it's running

• University Heart and Vascular Center Hamburg
  Hamburg, Germany Recruiting

Study contacts

• Principal investigator: Sebastian Ludwig, MD — Universitätsklinikum Hamburg-Eppendorf
• Study coordinator: Sebastian Ludwig, MD
• Email: se.ludwig@uke.de
• Phone: +49-40-7410-0

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• MRace Implant: A first look at fixing the mitral valve to reduce regurgitation

  This single-arm study tests whether the MRace Implant and Delivery System can safely place a prosthesis to reduce severe mitral regurgitation in high-risk patients who may not be good candidates for open-heart surgery.

  Recruiting at 4 sites Polares Medical SA · Tbilisi and 3 other locations · NCT07796659

• Mitral Valve Calcification Imaging with TrueVue 3D Light Rendering

  This study tests how well three-dimensional transesophageal echocardiography with TrueVue transillumination detects mitral valve calcifications compared with CT in adults.

  Recruiting Centro Cardiologico Monzino · Milan, Milan · NCT07612553

• Tracking progression and consequences of heart valve disease

  This project will follow adults with moderate or worse valve disease to see if clinical tests and imaging can predict when their condition will get worse.

  Recruiting at 15 sites Second Affiliated Hospital, Zhejiang University, School of Medicine · Fuzhou, Fujian and 14 other locations · NCT07267117

• Surgical implantation of a polymer prosthetic mitral or aortic valve

  This will test a surgically implanted polymer heart valve to see if it is safe and works well for adults who need mitral or aortic valve replacement.

  Recruiting Mitrassist Lifesciences Limited Co., Ltd. · Shanghai, Shanghai Municipality · NCT07097740

• Abbott Cephea registry for mitral valve disease

  Collects clinical information on adults with symptomatic mitral valve disease to see how correcting the valve with the Cephea system affects outcomes for patients who might be candidates for transcatheter mitral valve replacement.

  Recruiting at 24 sites Abbott Medical Devices · Birmingham, Alabama and 23 other locations · NCT07069673

• Using the CoolCryo System to treat Atrial Fibrillation during Mitral Valve Surgery

  This study is testing whether the CoolCryo system can safely help people with atrial fibrillation feel better during mitral valve surgery.

  Recruiting at 2 sites Medinice S.A. · Bydgoszcz and 1 other locations · NCT06557616

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.